长期的三维原发性上皮样细胞培养揭示了调节食管细胞健康的基因。 - Suppr | 超能文献

Long-term 3D primary epithelioid cultures reveal genes that regulate esophageal cell fitness.

出版信息

Nat Genet. 2024 Oct;56(10):2010-2011. doi: 10.1038/s41588-024-01887-4.

DOI:10.1038/s41588-024-01887-4

Abstract

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本文引用的文献

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Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth.Notch1 突变驱动正常食管上皮细胞的克隆扩张，但损害肿瘤生长。

Nat Genet. 2023 Feb;55(2):232-245. doi: 10.1038/s41588-022-01280-z. Epub 2023 Jan 19.

2

Somatic Mutation: What Shapes the Mutational Landscape of Normal Epithelia?体细胞突变：正常上皮细胞的突变景观由什么塑造？

Cancer Discov. 2022 Jul 6;12(7):1642-1655. doi: 10.1158/2159-8290.CD-22-0145.

3

Somatic cell-derived organoids as prototypes of human epithelial tissues and diseases.体细胞来源的类器官作为人类上皮组织和疾病的模型

Nat Mater. 2021 Feb;20(2):156-169. doi: 10.1038/s41563-020-0754-0. Epub 2020 Aug 17.

4

Esophageal 3D Culture Systems as Modeling Tools in Esophageal Epithelial Pathobiology and Personalized Medicine.食管3D培养系统作为食管上皮病理生物学和个性化医学中的建模工具

Cell Mol Gastroenterol Hepatol. 2018 Jan 31;5(4):461-478. doi: 10.1016/j.jcmgh.2018.01.011. eCollection 2018.