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社会经济地位与晚年抑郁:日常生活活动的纵向中介效应。

Socioeconomic status and depression in later life: longitudinal mediation effects of activities of daily living.

机构信息

Department of Health Management, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan, Guangdong, China.

School of Health Management, Southern Medical University, Guangzhou, Guangdong, China.

出版信息

BMC Psychiatry. 2024 Sep 27;24(1):625. doi: 10.1186/s12888-024-06077-4.

Abstract

BACKGROUND

Socioeconomic status (SES) is associated with both depression and activities of daily living (ADL and IADL). However, the role of ADL as a biological mechanism in the relationship between SES and late-life depression, examined through longitudinal data, remains understudied. This study explored the longitudinal mediation effects of basic ADL or IADL on the SES-depression link in older adults.

METHODS

Data from the China Health and Retirement Longitudinal Study (N = 4104) were utilized. Mediation analysis was performed using parallel process latent growth curve modeling.

RESULTS

The average age of participants was 57.76 years, and 55.7% being females. Significant linear growth over time was observed in ADL, IADL, and depression. Adjusting for covariates, SES was positively linked to the initial levels (intercepts) of ADL (β=-0.100[-0.143, -0.057]), IADL (β=-0.140[-0.185, -0.095]), and depression (β=-0.103[-0.158, -0.048]). However, SES showed no significant correlation with the rate of change (slopes) in ADL, IADL, or depression (P > 0.05). The intercepts of ADL (β = 0.566[0.503, 0.629]) and IADL (β = 0.607[0.544, 0.670]) were positively correlated with the depression intercept but negatively with the depression slope. Conversely, the slopes of ADL and IADL were positively associated with the depression slope. These results suggest a negative indirect relationship between SES and the initial level of depression, but a positive indirect relationship with the rate of increase in depression through ADL (or IADL) intercept.

CONCLUSIONS

Higher SES is associated with a lower initial risk of depression and ADL difficulties. However, this same higher SES may relate to a faster increase in ADL difficulties and depression among middle-aged and older adults. The findings underscore the need for increased governmental healthcare funding and improved healthcare accessibility. Additionally, maintaining adequate sleep and physical activity can help prevent disability and reduce depression risk later in life, particularly among older adults with lower SES.

摘要

背景

社会经济地位(SES)与抑郁和日常生活活动(ADL 和 IADL)都有关。然而,通过纵向数据检查 ADL 在 SES 与晚年抑郁之间的关系中的生物学机制作用仍研究不足。本研究探讨了基本 ADL 或 IADL 对老年人 SES 与抑郁关系的纵向中介效应。

方法

使用中国健康与退休纵向研究(N=4104)的数据。使用平行过程潜增长曲线模型进行中介分析。

结果

参与者的平均年龄为 57.76 岁,55.7%为女性。ADL、IADL 和抑郁均呈现出显著的随时间线性增长。调整协变量后,SES 与 ADL(β=-0.100[-0.143,-0.057])、IADL(β=-0.140[-0.185,-0.095])和抑郁(β=-0.103[-0.158,-0.048])的初始水平(截距)呈正相关。然而,SES 与 ADL、IADL 或抑郁的变化率(斜率)无显著相关性(P>0.05)。ADL(β=0.566[0.503,0.629])和 IADL(β=0.607[0.544,0.670])的截距与抑郁的截距呈正相关,但与抑郁的斜率呈负相关。相反,ADL 和 IADL 的斜率与抑郁的斜率呈正相关。这些结果表明 SES 与抑郁的初始水平呈负相关间接关系,但与通过 ADL(或 IADL)截距的抑郁增长率呈正相关间接关系。

结论

较高的 SES 与较低的初始抑郁风险和 ADL 困难有关。然而,同样较高的 SES 可能与中年和老年人的 ADL 困难和抑郁的增加速度更快有关。这些发现强调了需要增加政府医疗保健资金和改善医疗保健可及性。此外,保持充足的睡眠和身体活动可以帮助预防残疾和降低晚年的抑郁风险,特别是在 SES 较低的老年人中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43dc/11428304/6e3285c805ab/12888_2024_6077_Fig1_HTML.jpg

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