Department of Cardiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Department of Control and Prevention of Chronic Non-communicable Diseases, Xuzhou Center for Disease Control and Prevention, Xuzhou, China.
BMC Public Health. 2024 Sep 27;24(1):2645. doi: 10.1186/s12889-024-20066-y.
It is widely known that the incidence rate and short-term mortality of acute myocardial infarctions (AMIs) are generally higher during the winter months. The goal of this study was to determine how the temperature of the environment influences fatal acute myocardial infarctions in Xuzhou.
This observational study used the daily meteorological data and the data on the cause of death from acute myocardial infarction in Xuzhou from January 1, 2018, to December 31, 2020. After controlling meteorological variables and pollutants, the distributed nonlinear lag model (DLNM) was used to estimate the correlation between temperature and lethal AMI.
A total of 27,712 patients with fatal AMI were enrolled. 82.4% were over the age of 65, and 50.9% were men. Relative to the reference temperature (15 ℃), the 30-day cumulative RRs of the extremely cold temperature (- 2 ℃) for the general population, women, and people aged 65 years and above were 4.66 (95% CI: 1.76, 12.30), 15.29 (95% CI: 3.94, 59.36), and 7.13 (95% CI: 2.50, 20.35), respectively. The 30-day cumulative RRs of the cold temperature (2 ℃) for the general population, women, and people aged 65 years and above were 2.55 (1.37, 4.75), 12.78 (2.24, 5.36), and 3.15 (1.61, 6.16), respectively. No statistically significant association was observed between high temperatures and the risk of fatal AMI. The influence of the cold effect (1st and 10th) was at its peak on that day, and the entire cold effect persisted for 30 days. Temperature extremes had an effect on the lag patterns of distinct age and gender stratifications.
According to this study, the risk of fatal AMI increases significantly in cold weather but not in hot weather. Women above the age of 65 are particularly sensitive to severe weather events. The influence of frigid weather on public health should also be considered.
众所周知,急性心肌梗死(AMI)的发病率和短期死亡率通常在冬季较高。本研究旨在确定环境温度如何影响徐州的致命性急性心肌梗死。
本观察性研究使用了 2018 年 1 月 1 日至 2020 年 12 月 31 日期间徐州的每日气象数据和急性心肌梗死死因数据。在控制气象变量和污染物后,使用分布式非线性滞后模型(DLNM)来估计温度与致命性急性心肌梗死之间的相关性。
共纳入 27712 例致命性急性心肌梗死患者。82.4%的患者年龄超过 65 岁,50.9%为男性。与参考温度(15℃)相比,一般人群、女性和 65 岁及以上人群极低温(-2℃)的 30 天累积 RR 分别为 4.66(95%CI:1.76,12.30)、15.29(95%CI:3.94,59.36)和 7.13(95%CI:2.50,20.35)。一般人群、女性和 65 岁及以上人群低温(2℃)的 30 天累积 RR 分别为 2.55(1.37,4.75)、12.78(2.24,5.36)和 3.15(1.61,6.16)。高温与致命性急性心肌梗死风险之间无统计学关联。冷效应(第 1 天和第 10 天)的影响在当天达到峰值,整个冷效应持续 30 天。温度极值对不同年龄和性别分层的滞后模式有影响。
根据本研究,寒冷天气下致命性急性心肌梗死的风险显著增加,但炎热天气下则不然。65 岁以上的女性对恶劣天气事件尤为敏感。严寒天气对公共健康的影响也应予以考虑。