Han Xueying, Ma Rulin, He Jia, Yang Bo, Chen Silin, Wu Xuelian, Muhetaer Dilimulati, Ma Lanqing, Shen Shijie, Li Xiaoxue, Zuo Pengxiang, Guo Heng
Shihezi University School of Medicine, Shihezi, China.
Front Public Health. 2025 Aug 21;13:1615288. doi: 10.3389/fpubh.2025.1615288. eCollection 2025.
Meteorological factors and air pollutants are two important factors affecting hospitalisation for coronary heart disease. This study aims to investigate the effects of meteorological factors and air pollutants on the risk of coronary heart disease hospitalisation and their interactions in rural areas with heavy particulate matter pollution at the edge of the desert in southern Xinjiang.
In this study, patients with coronary heart disease who were hospitalized in Tangyi Town, Tumushuke City, Xinjiang Province, were selected as the study subjects, and the lagged effects of meteorological factors and air pollutants on the risk of coronary heart disease hospitalisation and their interactions were analysed by combining the distributional lag nonlinear model and the quasi-Poisson regression model.
The results showed that the associations between meteorological factors and air pollutant concentrations with the risk of coronary heart disease hospitalisation both showed non-linear and lagged effects. There was an antagonistic effect between mean daily temperature and PM and PM on the effect of coronary heart disease hospitalisation, with RERIs of -0.73 (95% CI: -2.63, -0.04), and -1.14 (95% CI: -1.93, -0.60), respectively. The relative risk of coronary heart disease hospitalisation in the low-temperature, high PM10 concentration environment was 1.53 (95% CI: 1.09, 2.13). The risk of hospitalization for coronary heart disease is increased by 30 and 19% in environments with low humidity and high PM and PM concentrations, respectively. There are also interactions between particulate matter and gaseous pollutants and between different gaseous pollutants.
This study suggests the need to necessity of management of multiple air pollutants and response to climate change, as well as the importance of implementing targeted preventive and control measures by the relevant authorities in according to meteorological and air pollution conditions, which can effectively reduce the hospitalization rate of patients with coronary heart disease.
气象因素和空气污染物是影响冠心病住院率的两个重要因素。本研究旨在探讨气象因素和空气污染物对新疆南部沙漠边缘重颗粒物污染农村地区冠心病住院风险的影响及其相互作用。
本研究选取在新疆维吾尔自治区图木舒克市唐驿镇住院的冠心病患者作为研究对象，结合分布滞后非线性模型和拟泊松回归模型，分析气象因素和空气污染物对冠心病住院风险的滞后效应及其相互作用。
结果表明，气象因素和空气污染物浓度与冠心病住院风险之间的关联均呈现非线性和滞后效应。日平均气温与PM及PM对冠心病住院效应之间存在拮抗作用，相对超额危险度分别为-0.73（95%可信区间：-2.63，-0.04）和-1.14（95%可信区间：-1.93，-0.60）。在低温、高PM10浓度环境下，冠心病住院的相对风险为1.53（95%可信区间：1.09，2.13）。在低湿度、高PM及PM浓度环境下，冠心病住院风险分别增加30%和19%。颗粒物与气态污染物之间以及不同气态污染物之间也存在相互作用。
本研究表明，有必要对多种空气污染物进行管理并应对气候变化，以及相关部门根据气象和空气污染状况实施针对性的预防和控制措施的重要性，这可以有效降低冠心病患者的住院率。
