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运用精益六西格玛方法降低导管相关血流感染。

Reducing catheter-related bloodstream infections using Lean Six Sigma methodology.

机构信息

Department of Biostatistics and Health Data Science, School of Medicine, Indiana University, Indianapolis, IN, 46202, USA.

Nursing Department, The Second Affiliated Hospital of Guangzhou, University of Chinese Medicine, Guangzhou, Guangdong, 510120, China.

出版信息

BMC Health Serv Res. 2024 Sep 27;24(1):1121. doi: 10.1186/s12913-024-11527-6.

Abstract

BACKGROUND

Central venous catheters (CVC) are used for dialysis in end-stage renal disease patients, presenting a significant risk for Catheter-Related Bloodstream Infections (CRBSI). While Lean Six Sigma has been effective in reducing CRBSI, its efficacy outside intensive care units (ICU) remains less explored. This study aims to evaluate the effectiveness of Lean Six Sigma in mitigating CRBSI risks among non-ICU hemodialysis patients.

METHODS

The study was conducted in a nephrology department, focusing on patients undergoing hemodialysis with temporary CVC from February to December 2021. The Lean Six Sigma method, using Define-Measure-Analyze-Improve-Control (DMAIC) methodology, was implemented in 2022 to reduce CRBSI incidence. The 2021 CRBSI rate served as the benchmark, with a goal to reduce it by the end of 2022. Value-stream mapping, Fishbone Diagrams, and Root Cause Analysis identified potential CRBSI causes. After implementing targeted improvements, CRBSI rates before and after the intervention were compared.

RESULTS

The Lean Six Sigma method significantly decreased CRBSI incidence from 12.79 to 2.32 per 1,000 catheter-days following the implementation of targeted interventions ([Formula: see text]=4.60, P = 0.05). This improvement was observed comparing February-December 2021 with January-December 2022.

CONCLUSION

The findings demonstrate the effectiveness of the Lean Six Sigma method in non-ICU settings, suggesting broader applicability in hemodialysis patient care.

摘要

背景

中心静脉导管(CVC)用于终末期肾病患者的透析,存在导管相关血流感染(CRBSI)的重大风险。虽然精益六西格玛在降低 CRBSI 方面已被证明是有效的,但它在重症监护病房(ICU)之外的疗效仍较少被探索。本研究旨在评估精益六西格玛在减轻非 ICU 血液透析患者 CRBSI 风险方面的有效性。

方法

该研究在肾病科进行,重点关注 2021 年 2 月至 12 月期间接受临时 CVC 血液透析的患者。2022 年采用精益六西格玛方法,使用定义-测量-分析-改进-控制(DMAIC)方法,以降低 CRBSI 的发生率。2021 年 CRBSI 发生率作为基准,目标是在 2022 年底前降低。价值流映射、鱼骨图和根本原因分析确定了潜在的 CRBSI 原因。在实施有针对性的改进后,比较了干预前后的 CRBSI 发生率。

结果

实施有针对性的干预后,CRBSI 发生率从每 1000 个导管日 12.79 例降至 2.32 例([公式:见文本]=4.60,P=0.05)。与 2021 年 2 月至 12 月相比,2022 年 1 月至 12 月观察到这一改善。

结论

研究结果表明,精益六西格玛方法在非 ICU 环境中是有效的,提示其在血液透析患者护理中有更广泛的适用性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12d7/11430130/0b8767e8ed0c/12913_2024_11527_Fig1_HTML.jpg

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