人工耳蜗植入对耳鸣的长期影响：一项系统评价和荟萃分析。

The Long-Term Effect of Cochlear Implantation on Tinnitus: A Systematic Review and Meta-Analysis.

作者信息

Li Yutian, Yang Huiwen, Niu Xun, Sun Yu

机构信息

Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Institute of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

出版信息

Diagnostics (Basel). 2024 Sep 13;14(18):2028. doi: 10.3390/diagnostics14182028.

DOI:10.3390/diagnostics14182028

PMID:39335707

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11431415/

Abstract

OBJECTIVE

This systematic review investigates the long-term effect of cochlear implantation (CI) on clinical outcomes in tinnitus patients with sensorineural hearing loss (SNHL).

DATABASE SOURCES

PubMed, Embase, and the Cochrane Library were searched from inception to 30 April 2024. Manual searches of reference lists supplemented these searches when necessary.

REVIEW METHODS

Original studies included in the meta-analysis had to contain comparative pre- and postoperative data for SNHL patients who underwent CI. Outcomes measured were the Tinnitus Handicap Inventory (THI), Visual Analog Scale (VAS), and Tinnitus Questionnaire (TQ).

RESULTS

A total of 28 studies comprising 853 patients showed significant tinnitus improvement after CI: THI mean difference (MD) -14.02 [95%CI -15.29 to -12.76, < 0.001], TQ MD -15.85 [95%CI -18.97 to -12.74, < 0.05], and VAS MD -3.12 [95%CI -3.49 to -2.76, < 0.05]. Subgroup analysis indicated a significant difference between follow-up periods in THI ( < 0.0001) and VAS loudness ( = 0.02).

CONCLUSIONS

Cochlear implantation substantially improves tinnitus in patients with hearing loss, though the effect may diminish over time. Further research is needed to confirm these findings.

摘要

目的

本系统评价旨在研究人工耳蜗植入（CI）对感音神经性听力损失（SNHL）耳鸣患者临床结局的长期影响。

数据库来源

检索了PubMed、Embase和Cochrane图书馆，检索时间从建库至2024年4月30日。必要时，通过手动检索参考文献列表对这些检索进行补充。

综述方法

纳入荟萃分析的原始研究必须包含接受CI的SNHL患者术前和术后的对比数据。测量的结局指标为耳鸣障碍量表（THI）、视觉模拟量表（VAS）和耳鸣问卷（TQ）。

结果

共有28项研究（853例患者）显示CI后耳鸣有显著改善：THI平均差（MD）为-14.02[95%CI -15.29至-12.76，<0.001]，TQ MD为-15.85[95%CI -18.97至-12.74，<0.05]，VAS MD为-3.12[95%CI -3.49至-2.76，<0.05]。亚组分析表明，THI随访期（<0.0001）和VAS响度（=0.02）之间存在显著差异。