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单侧假性男性乳房发育症一例独特病例。

A Unique Case of Unilateral Pseudogynecomastia.

作者信息

Kountouri Ismini, Katsarelas Ioannis, Kokkali Eftychia, Giotas Amyntas, Gkogkos Christos, Chatzinas Dimitrios, Nachopoulos Panagiotis, Faseki Afroditi, Panagiotou Alexandra, Polychronidis Athanasios, Chandolias Miltiadis, Gkiatas Nikolaos, Manolakaki Dimitra, Dimasis Periklis

机构信息

Department of General Surgery, General Hospital of Katerini, 60132 Pieria, Greece.

Department of Radiology, General Hospital of Katerini, 60132 Pieria, Greece.

出版信息

Diagnostics (Basel). 2024 Sep 17;14(18):2058. doi: 10.3390/diagnostics14182058.

DOI:10.3390/diagnostics14182058
PMID:39335737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11431527/
Abstract

BACKGROUND/OBJECTIVES: Gynecomastia is a common condition characterized by the benign enlargement of male breast tissue, often resulting from hormonal imbalances. A rare variant, unilateral pseudogynecomastia, involves enlargement due to adipose tissue accumulation without glandular proliferation and can be associated with occupational factors.

METHODS

We report the case of a 45-year-old male mechanic presenting with unilateral enlargement of the left breast. The patient reported daily microtrauma on his left axilla and chest wall. The clinical evaluation and imaging revealed lipomatosis with pronounced fibrous tissue and no glandular tissue involvement. The hormonal assays were within the normal limits. The patient underwent surgical excision of excess adipose tissue using the Kornstein technique, preserving the nipple-areola complex.

RESULTS

The histopathological examination confirmed the absence of malignancy. The postoperative recovery was uneventful, and the follow-up examination at 12 months demonstrated a symmetrical breast appearance with no recurrence. This case underscores the importance of differentiating pseudogynecomastia from true gynecomastia and recognizing potential occupational risks. Surgical management using techniques that preserve the nipple-areola complex can achieve excellent cosmetic outcomes.

摘要

背景/目的:男性乳房肥大是一种常见病症,其特征为男性乳腺组织的良性增生,通常由激素失衡引起。一种罕见的变异型,单侧假性男性乳房肥大,是由于脂肪组织堆积而导致的乳房增大,无腺体增生,且可能与职业因素有关。

方法

我们报告了一例45岁男性机械师,其左侧乳房出现单侧增大。患者自述左侧腋窝和胸壁每日受到微创伤。临床评估和影像学检查显示为脂肪瘤病,伴有明显的纤维组织,无腺体组织受累。激素检测结果在正常范围内。患者采用科恩斯坦技术接受了多余脂肪组织的手术切除,保留了乳头乳晕复合体。

结果

组织病理学检查证实无恶性病变。术后恢复顺利,12个月的随访检查显示乳房外观对称,无复发。该病例强调了区分假性男性乳房肥大与真性男性乳房肥大以及认识潜在职业风险的重要性。采用保留乳头乳晕复合体的技术进行手术治疗可取得极佳的美容效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/c16e2c5a25ff/diagnostics-14-02058-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/cfd2e87fe484/diagnostics-14-02058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/184835f22004/diagnostics-14-02058-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/cc9e82a7763d/diagnostics-14-02058-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/430ad428fe28/diagnostics-14-02058-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/c16e2c5a25ff/diagnostics-14-02058-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/cfd2e87fe484/diagnostics-14-02058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/184835f22004/diagnostics-14-02058-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/cc9e82a7763d/diagnostics-14-02058-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/430ad428fe28/diagnostics-14-02058-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4414/11431527/c16e2c5a25ff/diagnostics-14-02058-g005.jpg

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本文引用的文献

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Efficacy and Safety of Cold-Induced Noninvasive Targeted Fat Reduction in Pseudogynecomastia.冷诱导非侵入性靶向减脂治疗男性假性乳房肥大的疗效与安全性。
Ann Dermatol. 2022 Dec;34(6):412-418. doi: 10.5021/ad.21.180.
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An Alternative Treatment of Pseudogynecomastia in Male Patients After Massive Weight Loss.肥胖男性患者大量减重后假性男性乳房发育的一种替代治疗方法。
Aesthet Surg J Open Forum. 2020 May 16;2(2):ojaa013. doi: 10.1093/asjof/ojaa013. eCollection 2020 Jun.
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Prepubertal gynecomastia is not always idiopathic: case series and review of the literature.
青春期前男性乳腺发育并非总是特发性的:病例系列及文献复习。
Eur J Pediatr. 2021 Mar;180(3):977-982. doi: 10.1007/s00431-020-03799-x. Epub 2020 Sep 25.
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Is gynecomastia related to the disease characteristics and prognosis in testicular germ cell tumor patients?男性乳房发育症与睾丸生殖细胞肿瘤患者的疾病特征和预后有关吗?
Diagn Interv Radiol. 2019 May;25(3):189-194. doi: 10.5152/dir.2019.18297.
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Gynecomastia - Conservative and Surgical Management.男性乳房肥大症——保守治疗与手术治疗
Breast Care (Basel). 2018 Dec;13(6):419-424. doi: 10.1159/000494276. Epub 2018 Nov 14.
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A Teenager with Sudden Unilateral Breast Enlargement.一名突发单侧乳房增大的青少年。
J Pediatr. 2017 Mar;182:394. doi: 10.1016/j.jpeds.2016.11.044. Epub 2016 Dec 9.
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Unilateral gynecomastia in a tennis player.
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Enlarging unilateral breast mass in an adolescent male: an unusual presentation of intraductal papilloma.青春期男性单侧乳腺增大:导管内乳头状瘤的一种不常见表现。
J Pediatr Surg. 2011 May;46(5):e33-5. doi: 10.1016/j.jpedsurg.2011.02.068.
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Aesthetic Plast Surg. 2011 Apr;35(2):270-3. doi: 10.1007/s00266-010-9584-9. Epub 2010 Sep 17.
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