Wu Jing, Li Huilin, Wang Zhijuan, Pan Mingfei, Wang Shuo
Tianjin Key Laboratory of Food Science and Health, School of Medicine, Nankai University, Tianjin 300071, China.
State Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China.
Foods. 2024 Sep 21;13(18):2996. doi: 10.3390/foods13182996.
-butylhydroquinone (TBHQ) is a phenolic substance that is commonly employed to prevent food oxidation. Excessive or improper utilization of this antioxidant can not only impact food quality but may also pose potential risks to human health. In this study, an ultrasensitive, stable, and easily operable ratiometric electrochemical sensor was successfully fabricated by combining the tubular (3,4-ethylenedioxythiophene) (T-PEDOT) with single-wall carbon nanohorns (SWCNHs) for the detection of TBHQ antioxidants in food. The SWCNHs/T-PEDOT nanocomposite fabricated through ultrasound-assisted and template approaches was employed as the modified substrate for the electrode interface. The synergistic effect of SWCNHs and T-PEDOT, which possess excellent electrical conductivity and catalytic properties, enabled the modified electrode to showcase remarkable electrocatalytic performance towards TBHQ, with the redox signal of methylene blue serving as an internal reference. Under optimized conditions, the SWCNHs/T-PEDOT-modified electrode demonstrated good linearity within the TBHQ concentration range of 0.01-200.0 μg mL, featuring a low limit of detection (LOD) of 0.005 μg mL. The proposed ratiometric electrochemical sensor displayed favorable reproducibility, stability, and anti-interference capacity, thereby offering a promising strategy for monitoring the levels of TBHQ in oil-rich food products.
叔丁基对苯二酚（TBHQ）是一种常用于防止食品氧化的酚类物质。这种抗氧化剂的过量或不当使用不仅会影响食品质量，还可能对人体健康构成潜在风险。在本研究中，通过将管状（3,4-乙撑二氧噻吩）（T-PEDOT）与单壁碳纳米角（SWCNHs）相结合，成功制备了一种超灵敏、稳定且易于操作的比率型电化学传感器，用于检测食品中的TBHQ抗氧化剂。通过超声辅助和模板法制备的SWCNHs/T-PEDOT纳米复合材料被用作电极界面的修饰基底。具有优异导电性和催化性能的SWCNHs和T-PEDOT的协同作用，使修饰电极对TBHQ表现出显著的电催化性能，以亚甲基蓝的氧化还原信号作为内部参考。在优化条件下，SWCNHs/T-PEDOT修饰电极在0.01-200.0μg/mL的TBHQ浓度范围内表现出良好的线性，检测限低至0.005μg/mL。所提出的比率型电化学传感器具有良好的重现性、稳定性和抗干扰能力，从而为监测富含油脂食品中TBHQ的含量提供了一种有前景的策略。
