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季节性紊乱:大流行后耳鼻咽喉感染的趋势

Seasonality Disrupted: Post-Pandemic Trends in Otorhinolaryngological Infections.

作者信息

Pickert Julia, Riemann Sarah, Spörlein Andreas, Knopf Andreas

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Freiburg, Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Killlianstraße 5, 79106 Freiburg, Germany.

出版信息

J Clin Med. 2024 Sep 12;13(18):5388. doi: 10.3390/jcm13185388.

Abstract

The COVID-19 pandemic has notably affected the epidemiology of various infectious diseases. The imposed public health measures and disruptions in vaccination programs have potentially altered the patterns of these diseases post pandemic. To investigate the change in epidemiology of otorhinolaryngological infectious diseases in adult and pediatric patients after the COVID-19 pandemic and the relaxation of public health measures. A retrospective cohort study was conducted at a large tertiary university otolaryngology department in the south of Germany, examining admissions with specific ICD-10 diagnoses from 2019 to 2023. Data were seasonally categorized and statistically analyzed. A total of 1728 inpatient cases were analyzed. There was a significant increase in otorhinolaryngological infections in the post-pandemic winter of 2022, particularly of peritonsillar abscesses, acute tonsillitis and acute mastoiditis. No significant post-pandemic spike in mononucleosis was observed. The duration of hospitalization was shorter in 2022, and the median age of patients did not change significantly pre- versus post-pandemic. The study indicates a significant post-pandemic rise in otorhinolaryngological infections. Remarkably, the typical "dip" in infections during the summer months was not observed in the post pandemic years, possibly reflecting the impact of the termination of non-pharmaceutical interventions. Mononucleosis was the only infection not following this pattern.

摘要

新冠疫情显著影响了各种传染病的流行病学。实施的公共卫生措施以及疫苗接种计划的中断可能改变了疫情后这些疾病的流行模式。为了调查新冠疫情及公共卫生措施放宽后成人和儿童患者耳鼻咽喉科传染病流行病学的变化。在德国南部一所大型三级大学的耳鼻咽喉科进行了一项回顾性队列研究,检查了2019年至2023年具有特定国际疾病分类第十版(ICD - 10)诊断的住院病例。数据按季节分类并进行统计分析。共分析了1728例住院病例。2022年疫情后的冬季,耳鼻咽喉科感染显著增加,尤其是扁桃体周围脓肿、急性扁桃体炎和急性乳突炎。未观察到疫情后单核细胞增多症的显著激增。2022年住院时间较短,疫情前后患者的中位年龄没有显著变化。该研究表明疫情后耳鼻咽喉科感染显著增加。值得注意的是,在疫情后的年份中未观察到夏季感染典型的“低谷”,这可能反映了非药物干预措施终止的影响。单核细胞增多症是唯一未遵循这一模式的感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2be9/11432418/2a1df20ac57b/jcm-13-05388-g001.jpg

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