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使用Cordis Incraft超低轮廓血管内移植物进行腹主动脉瘤腔内修复术的早期和中期结果:高容量中心经验

Early and Mid-Term Results of Endovascular Aneurysm Repair with the Cordis Incraft Ultra-Low Profile Endograft: A High-Volume Center Experience.

作者信息

Baccani Luigi, Parlani Gianbattista, Isernia Giacomo, Lenti Massimo, Terpin Andrea Maria, Simonte Gioele

机构信息

Vascular and Endovascular Surgery Unit, S. Maria della Misericordia University Hospital, 06132 Perugia, Italy.

出版信息

J Clin Med. 2024 Sep 12;13(18):5413. doi: 10.3390/jcm13185413.

Abstract

: In recent years, manufacturers have developed new low-profile stent grafts to allow endovascular treatment of abdominal aortic aneurysms (AAA) in patients with small access vessels. We evaluated the early and mid-term outcomes of the Incraft (Cordis Corp, Bridgewater, NJ, USA) ultra-low profile endograft implantation in a high-volume single center. : Between 2014 and 2023, 133 consecutive endovascular aneurysm repair (EVAR) procedures performed using the Incraft endograft were recorded in a prospective database. Indications included infrarenal aortic aneurysms, common iliac aneurysms, and infrarenal penetrating aortic ulcers. Mid-term results were analyzed using the Kaplan-Meier method. : During the study period, 133 patients were treated with the Cordis Incraft endograft, in both elective and urgent settings. The Incraft graft was the first choice for patients with hostile iliac accesses, a feature characterizing at least one side in 90.2% of the patients in the study cohort. The immediate technical success rate was 78.2%. The intraoperative endoleak rate was 51.9% (20.3% type 1 A, 0.8% type 1 B, and 30.8% type 2 endoleak). Within 30 days, technical and clinical success rates were both 99.3%; all type 1A and 1B endoleaks were resolved at the 30-day follow-up CT-angiogram. After a mean follow-up of 35.4 months, the actuarial freedom from the re-intervention rate was 96.0%, 91.1%, and 84.0% at 1, 3, and 5 years, respectively. The iliac leg patency rate was 97.1%, 94.1%, and 93.1% at 1, 3, and 5 years, respectively. No statistically significant differences were observed between hostile and non-hostile access groups, nor between the groups with grade 1, grade 2, and grade 3 access hostility. : The ultra-low profile Cordis Incraft endograft represents a valid option for the endovascular treatment of AAA in patients with hostile iliac accesses. The procedure can be performed with high rates of technical and clinical success at 30 days and the rates of iliac branch occlusion observed during the follow-up period appear acceptable in patients with poor aorto-iliac outflow.

摘要

近年来,制造商开发了新型低轮廓支架移植物,以允许对入路血管较小的患者进行腹主动脉瘤(AAA)的血管内治疗。我们在一个高容量的单中心评估了Incraft(美国新泽西州布里奇沃特市科迪斯公司)超低轮廓腔内移植物植入的早期和中期结果。

在2014年至2023年期间,前瞻性数据库记录了133例连续使用Incraft腔内移植物进行的血管内动脉瘤修复(EVAR)手术。适应症包括肾下腹主动脉瘤、髂总动脉瘤和肾下穿透性主动脉溃疡。使用Kaplan-Meier方法分析中期结果。

在研究期间,133例患者在择期和急诊情况下接受了科迪斯Incraft腔内移植物治疗。Incraft移植物是髂动脉入路困难患者的首选,在研究队列中,90.2%的患者至少一侧具有这一特征。即刻技术成功率为78.2%。术中内漏率为51.9%(1A型20.3%,1B型0.8%,2型内漏30.8%)。30天内,技术成功率和临床成功率均为99.3%;所有1A型和1B型内漏在30天随访CT血管造影时均消失。平均随访35.4个月后,1年、3年和5年的再次干预率精算自由率分别为96.0%、91.1%和84.0%。髂支通畅率在1年、3年和5年时分别为97.1%、94.1%和93.1%。在髂动脉入路困难组和非困难组之间,以及在入路困难程度为1级、2级和3级的组之间,未观察到统计学上的显著差异。

超低轮廓的科迪斯Incraft腔内移植物是髂动脉入路困难的AAA患者血管内治疗的有效选择。该手术在30天时可实现较高的技术成功率和临床成功率,并且在随访期间观察到的髂支闭塞率在主-髂动脉流出道不佳的患者中似乎是可接受的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69f/11432392/02291071cf59/jcm-13-05413-g001.jpg

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