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腺样体切除术和扁桃体切除术患者中性粒细胞与淋巴细胞比值(NLR)、淋巴细胞与单核细胞比值(LMR)及血小板与淋巴细胞比值(PLR)的分析

The Analysis of Neutrophil to Lymphocyte Ratio (NLR), Lymphocyte to Monocyte Ratio (LMR), and Platelet to Lymphocyte Ratio (PLR) in Patients with Adenoidectomy and Tonsillectomy.

作者信息

Kim Jeong-Mi, Choi Jeong-Seok

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, College of Medicine, Inha University, 27 Inhang-ro, Jung-gu, Incheon 22332, Republic of Korea.

Research Center for Controlling Intercellular Communication (RCIC), College of Medicine, Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea.

出版信息

J Clin Med. 2024 Sep 14;13(18):5457. doi: 10.3390/jcm13185457.

Abstract

/ Adenoidectomy and tonsillectomy are among the most commonly performed procedures in ENT practice. The neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), and platelet-to-lymphocyte ratio (PLR) are recognized inflammatory markers. This study aims to evaluate the changes in NLR, PLR, and LMR in patients undergoing adenoidectomy and tonsillectomy. : The study group consisted of 980 patients who underwent adenoidectomy and/or tonsillectomy. Preoperative and postoperative inflammatory markers were measured in all patients. The NLR, LMR, and PLR values were then calculated and analyzed. In patients undergoing adenoidectomy and/or tonsillectomy, the postoperative NLR was significantly lower than the preoperative NLR. Similarly, the postoperative LMR was significantly higher, and the postoperative PLR was significantly lower compared to their preoperative values. The significant changes in NLR, LMR, and PLR following adenoidectomy and/or tonsillectomy suggest a reduction in systemic inflammation post-surgery. These findings indicate that these procedures may contribute to the improvement of inflammatory status in patients, highlighting the potential role of these markers in monitoring surgical outcomes.

摘要

腺样体切除术和扁桃体切除术是耳鼻喉科最常开展的手术之一。中性粒细胞与淋巴细胞比值(NLR)、淋巴细胞与单核细胞比值(LMR)以及血小板与淋巴细胞比值(PLR)是公认的炎症标志物。本研究旨在评估接受腺样体切除术和扁桃体切除术患者的NLR、PLR和LMR的变化。研究组由980例接受腺样体切除术和/或扁桃体切除术的患者组成。对所有患者术前和术后的炎症标志物进行测量。然后计算并分析NLR、LMR和PLR值。在接受腺样体切除术和/或扁桃体切除术的患者中,术后NLR显著低于术前NLR。同样,术后LMR显著升高,术后PLR显著低于术前值。腺样体切除术和/或扁桃体切除术后NLR、LMR和PLR的显著变化表明术后全身炎症减轻。这些发现表明,这些手术可能有助于改善患者的炎症状态,突出了这些标志物在监测手术结果方面的潜在作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/613d/11432515/7ddc71150e3e/jcm-13-05457-g001.jpg

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