Parness Shannon, Tasoudis Panagiotis, Agala Chris B, Merlo Aurelie E
Division of Cardiothoracic Surgery, Department of Surgery, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Department of Surgery, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
J Clin Med. 2024 Sep 15;13(18):5484. doi: 10.3390/jcm13185484.
Myocardial infarction (MI) is a leading cause of mortality globally and is predominantly attributed to coronary artery disease (CAD). MI is categorized as ST-elevation MI (STEMI) or non-ST-elevation MI (NSTEMI), each with distinct etiologies and treatment pathways. The goal in treatment for both is restoring blood flow back to the myocardium. STEMI, characterized by complete occlusion of a coronary artery, is managed urgently with reperfusion therapy, typically percutaneous coronary intervention (PCI). In contrast, NSTEMI involves a partial occlusion of a coronary artery and is treated with medical management, PCI, or coronary artery bypass grafting (CABG) depending on risk scores and clinical judgment. The Heart Team approach can assist in deciding which reperfusion technique would provide the greatest benefit to the patient and is especially useful in complicated cases. Despite advances in treatment, complications such as cardiogenic shock (CS) and ischemic heart failure (HF) remain significant. While percutaneous coronary intervention (PCI) is considered the primary treatment for MI, it is important to recognize the significance of cardiac surgery in treatment, especially when there is complex disease or MI-related complications. This comprehensive review analyzes the role of cardiac surgery in MI management, recognizing when it is useful, or not.
心肌梗死(MI)是全球主要的死亡原因,主要归因于冠状动脉疾病(CAD)。MI分为ST段抬高型心肌梗死(STEMI)或非ST段抬高型心肌梗死(NSTEMI),每种类型都有不同的病因和治疗途径。两者治疗的目标都是恢复心肌的血流。STEMI的特征是冠状动脉完全闭塞,通常通过再灌注治疗紧急处理,典型的是经皮冠状动脉介入治疗(PCI)。相比之下,NSTEMI涉及冠状动脉部分闭塞,根据风险评分和临床判断,采用药物治疗、PCI或冠状动脉旁路移植术(CABG)进行治疗。心脏团队方法有助于决定哪种再灌注技术对患者最有益,在复杂病例中尤其有用。尽管治疗取得了进展,但心源性休克(CS)和缺血性心力衰竭(HF)等并发症仍然很严重。虽然经皮冠状动脉介入治疗(PCI)被认为是MI的主要治疗方法,但认识到心脏手术在治疗中的重要性很重要,特别是在存在复杂疾病或与MI相关的并发症时。这篇综述分析了心脏手术在MI管理中的作用,确定其何时有用或无用。