Esposito Felice, Bove Ilaria, Vitulli Francesca, Bocchino Andrea, Barbanera Andrea, Nape Stefania, Lombardi Sara, Raffa Giovanni, Pintore Luigi, Palmiero Carmela, Fellico Fabrizio, Solari Domenico, Cavallo Luigi Maria, Somma Teresa
Department of Neurosciences and Reproductive and Dental Sciences, Division of Neurosurgery, Federico II University of Naples, 80131 Naples, Italy.
Division of Neurosurgery, Academic Hospital of Alessandria, 15121 Alessandria, Italy.
J Clin Med. 2024 Sep 19;13(18):5558. doi: 10.3390/jcm13185558.
To evaluate the efficacy of open and percutaneous pedicle screw fixation in the treatment of thoracolumbar fractures. Online databases MEDLINE (PubMed), SCOPUS, and Cochrane were searched for English language articles published between January 2001 and December 2023, limited to articles that included the clinical and radiological outcomes of adult patients. The main outcome measures of the study were the Oswestry Disability Index (ODI), the Numeric Rating Scale (NRS) score, and the Cobb angle. A total of 7 studies involving 909 patients were included; 374 (41.1%) procedures were performed with open surgery (OS), while 535 (58.9%) procedures were conducted with minimally invasive surgery (MIS). The mean value of ODI in the MIS group was 8.29% [CI 95% 4.82-11.76], compared to the other group, which was 14.22% (-value 0.87). Patients receiving a MIS had an average NRS of 1.54 [CI95% 0.98-2.10] whilst OS had 2.31 [CI95% 1.50-3.12] (-value 0.12). The percutaneous technique is equally safe and effective in resolving the deformity, but the clear advantages are represented by the reduction in blood loss, shorter operative times, a lower incidence of infection, shorter hospitalization, shorter postoperative rehabilitation, and therefore good results in terms of quality of life.
评估开放手术和经皮椎弓根螺钉固定术治疗胸腰椎骨折的疗效。检索在线数据库MEDLINE(PubMed)、SCOPUS和Cochrane,查找2001年1月至2023年12月发表的英文文章,仅限于包含成年患者临床和放射学结果的文章。该研究的主要结局指标为奥斯威斯利功能障碍指数(ODI)、数字评定量表(NRS)评分和Cobb角。共纳入7项研究,涉及909例患者;374例(41.1%)手术采用开放手术(OS),而535例(58.9%)手术采用微创手术(MIS)。MIS组ODI的平均值为8.29%[95%置信区间4.82 - 11.76],另一组为14.22%(P值0.87)。接受MIS的患者平均NRS为1.54[95%置信区间0.98 - 2.10],而OS组为2.31[95%置信区间1.50 - 3.12](P值0.12)。经皮技术在矫正畸形方面同样安全有效,但其明显优势在于减少失血、缩短手术时间、降低感染发生率、缩短住院时间、缩短术后康复时间,因此在生活质量方面取得良好效果。