Genowska Agnieszka, Zarębska-Michaluk Dorota, Dobrowolska Krystyna, Kanecki Krzysztof, Goryński Paweł, Tyszko Piotr, Lewtak Katarzyna, Rzymski Piotr, Flisiak Robert
Department of Public Health, Medical University of Bialystok, 15-295 Bialystok, Poland.
Department of Infectious Diseases and Allergology, Jan Kochanowski University, 25-317 Kielce, Poland.
J Clin Med. 2024 Sep 22;13(18):5618. doi: 10.3390/jcm13185618.
Analyzing hospitalizations of patients with hepatitis C virus (HCV) infection is essential for an effective action plan to eliminate hepatitis C as a public health threat. This study aimed to explore trends in hospitalizations of patients with HCV infection and factors related to these hospitalizations. This 11-year retrospective study (2012-2022) explored trends in hospitalizations of patients with HCV infection in Poland based on data from the Nationwide General Hospital Morbidity Study. : The mean age of individuals was 55 years, with hospitalization rates among men and women of 15.5 and 13.7 per 100,000 population, respectively. Hospitalizations were 1.8-fold higher among urban residents. The most frequent comorbidities were digestive (24%) and cardiovascular (18%) diseases. During the studied period, the hospitalization rates significantly decreased from 31.9 per 100,000 in 2012 to 5.0 per 100,000 in 2022, with stays requiring 0-3, 4-7, and ≥8 days becoming 8-fold, 6-fold, and 4-fold less frequent, respectively. The flattening of hospitalizations was apparent across all age groups, including children. : While significant progress has been made in managing HCV in Poland, continued efforts are required to eliminate disparities in care and to sustain the momentum toward HCV elimination, particularly through enhanced political commitment and the implementation of comprehensive national screening programs.
分析丙型肝炎病毒（HCV）感染患者的住院情况对于制定有效的行动计划以消除丙型肝炎这一公共卫生威胁至关重要。本研究旨在探讨HCV感染患者的住院趋势以及与这些住院情况相关的因素。这项为期11年的回顾性研究（2012 - 2022年）基于全国综合医院发病率研究的数据，探讨了波兰HCV感染患者的住院趋势。个体的平均年龄为55岁，男性和女性的住院率分别为每10万人口15.5例和13.7例。城市居民的住院率高出1.8倍。最常见的合并症是消化系统疾病（24%）和心血管疾病（18%）。在研究期间，住院率从2012年的每10万人口31.9例显著下降至2022年的每10万人口5.0例，住院时长为0 - 3天、4 - 7天和≥8天的情况分别减少了8倍、6倍和4倍。所有年龄组（包括儿童）的住院率下降趋势均很明显。虽然波兰在丙型肝炎管理方面取得了显著进展，但仍需继续努力消除护理方面的差距，并保持消除丙型肝炎的势头，特别是通过加强政治承诺和实施全面的国家筛查计划。
