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一个与大肠杆菌中果糖-1,6-二磷酸醛缩酶活性表达相关的新基因。

A new gene involved in expression of fructose-1,6-diphosphate aldolase activity in Escherichia coli.

作者信息

Atherly A G, Russell P

出版信息

Can J Microbiol. 1979 Aug;25(8):937-9. doi: 10.1139/m79-141.

Abstract

A new gene, fdaB, has been mapped by transduction and partial diploid analyses and located adjacent to argA at 59.9 min on the Escherichia coli recalibrated linkage map. This gene is involved in expression of fructose-1,6-diphosphate aldolase activity and indirectly in ribosomal RNA synthesis. The temperature-sensitive mutant strain AA-157, containing the defective gene product of of fdaB, accumulates high concentrations of fructose 1,6-diphosphate at the nonpermissive temperature.

摘要

一个新基因fdaB已通过转导和部分二倍体分析进行了定位,位于大肠杆菌重新校准的连锁图谱上59.9分钟处,与argA相邻。该基因参与1,6-二磷酸果糖醛缩酶活性的表达,并间接参与核糖体RNA的合成。温度敏感突变株AA-157含有缺陷的fdaB基因产物,在非允许温度下会积累高浓度的1,6-二磷酸果糖。

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