Carvalho Mariana de Oliveira, Duque Alice Pereira, Huguenin Grazielle Vilas Bôas, Felix Mediano Mauro Felippe, Rodrigues Júnior Luiz Fernando
Education and Research Department, National Institute of Cardiology, Rio de Janeiro 22240-002, RJ, Brazil.
Nutrition and Dietetics Department, Fluminense Federal University, Niterói 24020-140, RJ, Brazil.
Life (Basel). 2024 Sep 18;14(9):1174. doi: 10.3390/life14091174.
The coexistence of obesity and low muscle strength-denoted dynapenic obesity (DO)-has been associated with an unhealthy metabolic profile and increased risk for metabolic syndrome. However, there is a lack on studies investigating if DO exhibits higher cardiometabolic risk than non-dynapenic obesity. To assess if individuals with DO exhibit elevated cardiometabolic risk compared to non-dynapenic obesity. a cross-sectional study that analyzed the data of workers from a quaternary care hospital collected between November 2018 and March 2020. Participants were stratified into the following anthropometrical and peripheral muscle strength profiles: non-obese/non-dynapenic (NOND), non-obese/dynapenic (NOD), obese/non-dynapenic (OND), and obese dynapenic (OD). Cardiovascular risk was evaluated by Atherogenic Index (AI), Plasma Atherogenic Index (PAI), Hypertriglyceridemic Waist (HW), A Body Shape Index (ABSI), Atherogenic Dyslipidemia (AD), Castelli Indices I and II, and Framingham Score (FS). the OD group had significantly lower HDL compared to all others ( = 0.009), and despite exhibited lower prevalence of HW compared to OND ( < 0.01), a higher cardiometabolic risk compared to OND profile was observed assessing AI ( = 0.05), Castelli I ( < 0.05) and Castelli II ( < 0.05) scores. in the studied population, individuals with DO exhibit elevated cardiometabolic risk compared to other anthropometrical and peripheral muscle strength profiles.
肥胖与低肌肉力量并存（即肌无力性肥胖，DO），与不健康的代谢状况及代谢综合征风险增加有关。然而，缺乏研究来探究肌无力性肥胖是否比非肌无力性肥胖具有更高的心脏代谢风险。为评估与非肌无力性肥胖相比，肌无力性肥胖个体是否具有更高的心脏代谢风险，我们进行了一项横断面研究，分析了2018年11月至2020年3月期间从一家四级护理医院收集的工作人员数据。参与者被分为以下人体测量和外周肌肉力量类型：非肥胖/非肌无力（NOND）、非肥胖/肌无力（NOD）、肥胖/非肌无力（OND）和肥胖肌无力（OD）。通过致动脉粥样硬化指数（AI）、血浆致动脉粥样硬化指数（PAI）、高甘油三酯性腰围（HW）、体型指数（ABSI）、致动脉粥样硬化血脂异常（AD）、卡斯泰利指数I和II以及弗雷明汉评分（FS）来评估心血管风险。OD组的高密度脂蛋白水平显著低于其他所有组（P = 0.009），尽管与OND组相比HW患病率较低（P < 0.01），但在评估AI（P = 0.05）、卡斯泰利I（P < 0.05）和卡斯泰利II（P < 0.05）评分时，观察到OD组的心脏代谢风险高于OND组。在研究人群中，与其他人体测量和外周肌肉力量类型相比，肌无力性肥胖个体表现出更高的心脏代谢风险。
