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IgE介导的豆类过敏:儿科视角

IgE-Mediated Legume Allergy: A Pediatric Perspective.

作者信息

Mastrorilli Carla, Chiera Fernanda, Arasi Stefania, Giannetti Arianna, Caimmi Davide, Dinardo Giulio, Gracci Serena, Pecoraro Luca, Miraglia Del Giudice Michele, Bernardini Roberto

机构信息

Department of Pediatrics, University Hospital Consortium Corporation Polyclinic of Bari, Pediatric Hospital Giovanni XXIII, 70124 Bari, Italy.

Pediatric Unit, Giovanni Paolo II Hospital, ASP Catanzaro, 88046 Lamezia Terme, Italy.

出版信息

J Pers Med. 2024 Aug 25;14(9):898. doi: 10.3390/jpm14090898.

Abstract

Legumes are an inexpensive and essential protein source worldwide. The most consumed legumes include peanuts, soybeans, lentils, lupines, peas, common bean and chickpeas. In addition, the food industry is growing interested in expanding the use of legumes to partially replace or substitute cereals. Legumes were described to cause IgE-mediated allergies, and their growing use may also increase the incidence of allergy. The epidemiology of legume allergy varies by region; peanuts and soybeans are the legumes most involved in food allergies in Western countries, whereas lentils, peas, and chickpeas are reported as culprit allergens mainly in the Mediterranean area and India. This review, edited by the Italian Society of Pediatric Allergology and Immunology, summarizes the scientific literature on legume allergy in children and proposes a diagnostic workup and therapeutic approach.

摘要

在全球范围内,豆类是一种价格低廉且不可或缺的蛋白质来源。食用最为广泛的豆类包括花生、大豆、小扁豆、羽扇豆、豌豆、菜豆和鹰嘴豆。此外,食品行业越来越有兴趣扩大豆类的使用,以部分替代谷物。据描述,豆类会引发免疫球蛋白E(IgE)介导的过敏反应,其使用的增加也可能会提高过敏的发生率。豆类过敏的流行病学因地区而异;在西方国家,花生和大豆是食物过敏中最常涉及的豆类,而在地中海地区和印度,小扁豆、豌豆和鹰嘴豆则被报告为主要的致敏原。这篇由意大利儿童过敏与免疫学会编辑的综述总结了关于儿童豆类过敏的科学文献,并提出了诊断检查和治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc28/11433522/2f23ba505ba5/jpm-14-00898-g001.jpg

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