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肿瘤型人工关节置换中无骨水泥定制空心柄——保护儿童相邻关节的好机会?

Uncemented Customized Hollow Stems in Tumor Endoprosthetic Replacement-A Good Opportunity to Protect the Adjacent Joint in Children?

作者信息

Öztürk Recep, Streitbürger Arne, Hardes Jendrik, Hauschild Gregor, Guder Wiebke K, Podleska Lars Erik, Nottrott Markus, Engel Nina Myline

机构信息

Department of Orthopedic Oncology, University Hospital Essen, 45147 Essen, Germany.

出版信息

J Pers Med. 2024 Aug 29;14(9):919. doi: 10.3390/jpm14090919.

Abstract

This study aimed to retrospectively analyze the follow-up results of cases in which the adjacent joint was preserved using a custom-made uncemented short-stem design (hollow stem) with optional external flanches in tumor endoprosthetic replacement due to bone sarcomas in 13 patients (with an average age of 9.6 years) between 2017 and 2023. Reconstructions were proximal femur ( = 6), intercalary femur ( = 4), intercalary tibia ( = 2), and proximal humerus ( = 1) tumor prostheses. The hollow body was used distally in 10 of the megaprotheses, proximally in 1, and both proximally and distally in 2 of them. The average distance from the joints was 6 cm in stems with flanches and 11.8 cm in stems without flanches. No aseptic loosening or deep infection was observed during an average follow-up of 34 months. Except for one case with a tibial intercalary prosthesis that needed a revision, all cases were well osteointegrated and all lower extremity cases could bear full weight without pain. In cases where the remaining bone stock after bone resection is insufficient for a standard stem implantation, reconstruction with a patient-specific short hollow-stem design appears to be a good alternative to protect healthy joints with high prosthesis survival and low revision rates in the short-term follow-up.

摘要

本研究旨在回顾性分析2017年至2023年间13例(平均年龄9.6岁)因骨肉瘤行肿瘤假体置换时采用定制非骨水泥短柄设计(空心柄)并可选外部侧翼保留相邻关节的病例的随访结果。重建的是股骨近端(n = 6)、股骨中段(n = 4)、胫骨中段(n = 2)和肱骨近端(n = 1)肿瘤假体。10个大型假体在远端使用空心体,1个在近端使用,2个在近端和远端均使用。有侧翼柄与关节的平均距离为6 cm,无侧翼柄的为11.8 cm。平均随访34个月期间未观察到无菌性松动或深部感染。除1例胫骨中段假体需要翻修外,所有病例均骨整合良好,所有下肢病例均可完全负重且无疼痛。在骨切除后剩余骨量不足以植入标准柄的情况下,采用患者特异性短空心柄设计进行重建似乎是一种很好的选择,可在短期随访中保护健康关节,假体生存率高且翻修率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abe4/11433051/2a7fb05db77d/jpm-14-00919-g001.jpg

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