Valerio Jose, Borro Matteo, Proietti Elisa, Pisciotta Livia, Olarinde Immanuel O, Fernandez Gomez Maria, Alvarez Pinzon Andres Mauricio
Neurosurgery Oncology Center of Excellence, Neurosurgery Department, Miami Neuroscience Center at Larkin, South Miami, FL 33143, USA.
Internal Medicine Unit, Department of Internal Medicine, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132 Genova, Italy.
J Pers Med. 2024 Aug 31;14(9):929. doi: 10.3390/jpm14090929.
Recent scientific research has shown that the ketogenic diet may have potential benefits in a variety of medical fields, which has led to the diet receiving a substantial amount of attention. Clinical and experimental research on brain tumors has shown that the ketogenic diet has a satisfactory safety profile. This safety profile has been established in a variety of applications, including the management of obesity and the treatment of drug-resistant epileptic cases. However, in human studies, the impact of ketogenic therapy on the growth of tumors and the life expectancy of patients has not provided results that are well characterized. Consequently, our purpose is to improve the comprehension of these features by succinctly presenting the developments and conclusions that have been gained from the most recent study that pertains to this non-pharmacological technique. According to the findings of our study, patients with brain tumors who stick to a ketogenic diet are more likely to experience improved survival rates. However, it is required to conduct additional research on humans in order to more accurately define the anti-tumor efficiency of this diet as well as the underlying processes that support the therapeutic effects of this dieting regimen.
近期的科学研究表明,生酮饮食在多个医学领域可能具有潜在益处,这使得该饮食受到了大量关注。对脑肿瘤的临床和实验研究表明,生酮饮食具有令人满意的安全性。这种安全性已在多种应用中得到证实,包括肥胖管理和耐药性癫痫病例的治疗。然而,在人体研究中,生酮疗法对肿瘤生长和患者预期寿命的影响尚未得出明确的结果。因此,我们的目的是通过简要介绍从最近这项关于该非药物技术的研究所获得的进展和结论,来提高对这些特征的理解。根据我们的研究结果,坚持生酮饮食的脑肿瘤患者更有可能提高生存率。然而,需要对人体进行更多研究,以便更准确地确定这种饮食的抗肿瘤效果以及支持这种饮食疗法治疗效果的潜在机制。