Firmino Sabrina Santos, Santos-Doni Thaís Rabelo, Silva Vitória Maria Farias, Micheleto Aressa Cassemiro, de Souza Ma Scalise, Hortêncio Bruna Lima, Benitez Aline do Nascimento, Bento Yasmin Melim, Debortoli Gabriele Zaine Teixeira, Gomes Jancarlo Ferreira, Navarro Italmar Teodorico, Bresciani Katia Denise Saraiva
Faculdade de Medicina Veterinária, Universidade Estadual Paulista (UNESP), Araçatuba 16050-680, São Paulo, Brazil.
Instituto de Ciências Agrárias (ICA), Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Avenida Universitária, Unaí 38610-000, Minas Gerais, Brazil.
Microorganisms. 2024 Sep 6;12(9):1844. doi: 10.3390/microorganisms12091844.
This study examined the seropositivity of and coinfections with other TORCH pathogens among pregnant women attending 17 Basic Health Units (UBS) in Araçatuba, SP, Brazil. Of the 711 pregnant women seen at these UBS, only 297 were tested for . Of the women tested for ( = 297), 26.9% had IgG antibodies, 6.7% had IgM, and 32.0% tested positive for either or both. Only 1.4% showed both IgG and IgM antibodies, while 67.7% were non-reactive. The seropositivity was 17.1% for syphilis, 63.2% for rubella, 0.9% for hepatitis C, 0.9% for dengue, 17.9% for COVID-19, and 0.9% for herpes simplex (types 1/2). Coinfections with syphilis, rubella, and herpes simplex were also noted. Higher education levels appeared to protect against seropositivity. The findings highlight a significant prevalence of among pregnant women, with variation across UBSs, pointing to socioeconomic, behavioral, and environmental factors as influential. We also observed co-occurrence with other infections, such as syphilis, rubella, and herpes simplex. The study underscores the need for targeted public health interventions to reduce the risks of congenital infections.
本研究调查了巴西圣保罗州阿拉萨图巴市17个基本卫生单位（UBS）的孕妇中弓形虫血清阳性情况以及与其他TORCH病原体的合并感染情况。在这些基本卫生单位就诊的711名孕妇中，只有297人接受了弓形虫检测。在接受弓形虫检测的妇女（n = 297）中，26.9%有IgG抗体，6.7%有IgM抗体，32.0%的检测结果为单项或两项均呈阳性。只有1.4%同时显示IgG和IgM抗体，而67.7%无反应。梅毒血清阳性率为17.1%，风疹为63.2%，丙型肝炎为0.9%，登革热为0.9%，新冠病毒为17.9%，单纯疱疹（1/2型）为0.9%。还发现了梅毒、风疹和单纯疱疹的合并感染情况。较高的教育水平似乎可预防弓形虫血清阳性。研究结果突出了孕妇中弓形虫感染的高流行率，各基本卫生单位存在差异，表明社会经济、行为和环境因素具有影响作用。我们还观察到与梅毒、风疹和单纯疱疹等其他感染的共同发生情况。该研究强调需要采取有针对性的公共卫生干预措施，以降低先天性感染的风险。
