牙买加孕妇弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒（TORCH）及梅毒的血清学阳性率。

Seroprevalence of toxoplasma gondii, rubella virus, cytomegalovirus herpes simplex virus (TORCH) and syphilis in Jamaican pregnant women.

作者信息

Prabhakar P, Bailey A, Smikle M F, McCaw-Binns A, Ashley D

机构信息

Department of Microbiology, U.W.I., Jamaica.

出版信息

West Indian Med J. 1991 Dec;40(4):166-9.

PMID:1664562

Abstract

Seroprevalence of toxoplasma gondii, rubella virus, cytomegalovirus, herpes simplex virus infections (TORCH) and syphilis were determined in order to assess the immune/susceptibility status in Jamaican pregnant women in 1986. The positive rates were 57% (T. gondii), 69% (rubella), 97% (CMV), 91% (HSV), and 4.9% (syphilis), respectively. The rate of reactivity for syphilis ranged from 2.1% in Kingston and St. Andrew to 7.3% in rural parishes. The seropositivity rate for rubella was over 50% in all parishes, the highest being 85% in St. Thomas. The seroprevalence of T. gondii was lowest in Trelawny (37.5%). There were no significant differences in seropositivity of CMV and HSV infections between women from various parishes. The importance of seroprevalence of the TORCH group of agents and syphilis on perinatal morbidity and mortality in Jamaican women is discussed, and appropriate recommendations for prevention and control of congenital infections in Jamaica are suggested.

摘要

为评估1986年牙买加孕妇的免疫/易感性状况，对弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒感染（TORCH）及梅毒的血清阳性率进行了测定。其阳性率分别为57%（弓形虫）、69%（风疹）、97%（巨细胞病毒）、91%（单纯疱疹病毒）和4.9%（梅毒）。梅毒反应率在金斯敦和圣安德鲁为2.1%，在农村教区为7.3%。风疹血清阳性率在所有教区均超过50%，最高的是圣托马斯教区，为85%。弓形虫血清阳性率在特里洛尼最低（37.5%）。不同教区妇女的巨细胞病毒和单纯疱疹病毒感染血清阳性率无显著差异。文中讨论了TORCH组病原体和梅毒的血清阳性率对牙买加妇女围产期发病率和死亡率的重要性，并针对牙买加先天性感染的预防和控制提出了适当建议。