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一种用于测试血管和肠组织样本拉伸强度和弹性的定制设备,用于吻合口再生研究。

A Custom-Developed Device for Testing Tensile Strength and Elasticity of Vascular and Intestinal Tissue Samples for Anastomosis Regeneration Research.

机构信息

Department of Information Technology, Faculty of Informatics, University of Debrecen, Kassai Str. 26, H-4028 Debrecen, Hungary.

Department of Operative Techniques and Surgical Research, Faculty of Medicine, University of Debrecen, Moricz Zsigmond Str. 22, H-4032 Debrecen, Hungary.

出版信息

Sensors (Basel). 2024 Sep 15;24(18):5984. doi: 10.3390/s24185984.

DOI:10.3390/s24185984
PMID:39338729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11435504/
Abstract

Optimizing the regeneration process of surgically created anastomoses (blood vessels, intestines, nerves) is an important topic in surgical research. One of the most interesting parameter groups is related to the biomechanical properties of the anastomoses. Depending on the regeneration process and its influencing factors, tensile strength and other biomechanical features may change during the healing process. Related to the optimal specimen size, the range and accuracy of measurements, and applicability, we have developed a custom-tailored microcontroller-based device. In this paper, we describe the hardware and software configuration of the latest version of the device, including experiences and comparative measurements of tensile strength and elasticity of artificial materials and biopreparate tissue samples. The machine we developed was made up of easily obtainable parts and can be easily reproduced on a low budget. The basic device can apply a force of up to 40 newtons, and can grasp a 0.05-1 cm wide, 0.05-1 cm thick tissue. The length of the test piece on the rail should be between 0.3 and 5 cm. Low production cost, ease of use, and detailed data recording make it a useful tool for experimental surgical research.

摘要

优化手术吻合口(血管、肠道、神经)的再生过程是外科研究中的一个重要课题。其中最有趣的参数组之一与吻合口的生物力学特性有关。根据再生过程及其影响因素,在愈合过程中,拉伸强度和其他生物力学特征可能会发生变化。与最佳样本大小、测量范围和准确性以及适用性相关,我们开发了一种定制的基于微控制器的设备。本文介绍了该设备最新版本的硬件和软件配置,包括对人工材料和生物组织样本的拉伸强度和弹性的经验和比较测量。我们开发的机器由易于获得的部件组成,可以在低预算的情况下轻松复制。基本设备可以施加高达 40 牛顿的力,并可以夹持 0.05-1 厘米宽、0.05-1 厘米厚的组织。轨道上试件的长度应在 0.3 至 5 厘米之间。低制造成本、易于使用和详细的数据记录使其成为实验性外科研究的有用工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/931ebf3b00ee/sensors-24-05984-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/d59fe1703cb3/sensors-24-05984-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/2c225d4a966f/sensors-24-05984-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/95d24f5804bd/sensors-24-05984-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/57a986c5d523/sensors-24-05984-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/ddd25063bb47/sensors-24-05984-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/931ebf3b00ee/sensors-24-05984-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/d59fe1703cb3/sensors-24-05984-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/2c225d4a966f/sensors-24-05984-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/95d24f5804bd/sensors-24-05984-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/57a986c5d523/sensors-24-05984-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/ddd25063bb47/sensors-24-05984-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a061/11435504/931ebf3b00ee/sensors-24-05984-g006.jpg

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Effect of Nonlinear Hyperelastic Property of Arterial Tissues on the Pulse Wave Velocity Based on the Unified-Fiber-Distribution (UFD) Model.基于统一纤维分布(UFD)模型的动脉组织非线性超弹性特性对脉搏波速度的影响
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