Lukić Milica, Ćirić Ana, Božić Dragana D, Stanković Jelena Antić, Medarević Đorđe, Maksimović Zoran
Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.
Department of Immunology and Microbiology, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.
Pharmaceutics. 2024 Sep 7;16(9):1182. doi: 10.3390/pharmaceutics16091182.
Agricultural waste is underutilized, and sometimes burning them has a negative impact on the environment and human health. This research investigates the untapped potential of extracts from maize, wheat and sunflower waste as natural materials for cutaneous, specifically, cosmetic application. The possibility of incorporating lipid and ethanol extracts from wheat, maize, and sunflower into creams was investigated together with their potential contribution to the structural and functional properties of the topical formulations. Results of the physicochemical characterization show that investigated extracts can be successfully incorporated into creams with satisfactory stability. All extracts showed a desirable safety profile and good antimicrobial activity against various microorganisms. Lipid extracts have proven to be promising structural ingredients of the oil phase, contributing to the spreadability, occlusivity, and emollient effect. Ethanol extracts influenced washability and stickiness of the formulation and could be considered as prospective ingredients in self-preserving formulations. The extracts affected the sensory properties of the creams, mainly the smell and color. These results suggest that the extracts from wheat, maize, and sunflower waste could be used as multifunctional natural ingredients for cosmetic formulations which can replace less sustainable raw materials. This also represents a valorization of waste and is in line with broader sustainability goals.
农业废弃物未得到充分利用,有时焚烧这些废弃物会对环境和人类健康产生负面影响。本研究调查了玉米、小麦和向日葵废弃物提取物作为天然材料在皮肤应用,特别是化妆品应用方面尚未开发的潜力。研究了将小麦、玉米和向日葵的脂质提取物和乙醇提取物加入乳膏中的可能性,以及它们对局部制剂结构和功能特性的潜在贡献。物理化学表征结果表明,所研究的提取物能够成功地加入乳膏中,且稳定性良好。所有提取物均显示出理想的安全性,并对多种微生物具有良好的抗菌活性。脂质提取物已被证明是油相中有前景的结构成分,有助于铺展性、封闭性和润肤效果。乙醇提取物影响制剂的可洗性和粘性,可被视为自防腐制剂中的潜在成分。提取物影响了乳膏的感官特性,主要是气味和颜色。这些结果表明,小麦、玉米和向日葵废弃物的提取物可作为多功能天然成分用于化妆品配方,从而取代可持续性较差的原材料。这也体现了对废弃物的价值利用,符合更广泛的可持续发展目标。