Central Florida Zoo & Botanical Gardens' Orianne Center for Indigo Conservation, 30931 Brantley Branch Road, Eustis, FL 32736, USA.
Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA.
Viruses. 2024 Sep 21;16(9):1496. doi: 10.3390/v16091496.
A breeding colony of wild-origin eastern indigo snakes (EISs, ) that is part of a reintroduction program has been impacted by gastric cryptosporidiosis. Gastric cryptosporidiosis is an insidious disease of squamates caused by an apicomplexan protozoan, . Viral coinfections have been implicated as possible immunosuppressant agents that allow for disease progression and both adenovirus and reovirus have been implicated in allowing for the progression of gastric cryptosporidiosis during coinfection in other snake species. Molecular (PCR) screening for adenoviruses and reoviruses was performed for both -positive and -negative EIS within the breeding colony. No reoviruses were detected in the collection. Adenoviruses were present in 11/68 (16.2%) EISs evaluated, and there was no significant difference between -positive and -negative EISs ( = 0.196). There was no significant difference in adenovirus status between -positive EISs' lifespan ( = 0.191) or survival rates ( = 0.823). These findings suggest that the presence of the adenoviruses found in this study does not contribute to the formation or progression of gastric cryptosporidiosis in EISs.
一个野生东部靛青蛇（EIS）的繁殖群体，是重新引入计划的一部分，受到了胃隐孢子虫病的影响。胃隐孢子虫病是一种由顶复门原生动物引起的蜥蜴隐孢子虫病。病毒合并感染被认为是可能的免疫抑制剂，允许疾病进展，腺病毒和呼肠孤病毒都被认为在其他蛇种的合并感染中允许胃隐孢子虫病的进展。对繁殖群体中的 -阳性和 -阴性 EIS 进行了腺病毒和呼肠孤病毒的分子（PCR）筛选。在该采集物中未检测到呼肠孤病毒。腺病毒存在于 68 个 EIS 中的 11 个（16.2％）中，-阳性和 -阴性 EIS 之间没有显着差异（= 0.196）。-阳性 EIS 的寿命（= 0.191）或存活率（= 0.823）之间的腺病毒状态没有显着差异。这些发现表明，本研究中发现的腺病毒的存在不会导致 EIS 胃隐孢子虫病的形成或进展。
