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2021年至2023年德国风险群体中关于新冠疫情消退期间对流感和肺炎球菌疫苗接种态度变化的纵向调查研究结果

Changes in Attitudes towards Influenza and Pneumococcal Vaccination during the Subsiding COVID-19 Pandemic-Results of a Longitudinal Survey Study among Risk Groups in Germany between 2021 and 2023.

作者信息

Born Sebastian, Schwarzkopf Daniel, Rose Norman, Pletz Mathias W, Reinhart Konrad, Fleischmann-Struzek Carolin

机构信息

Institute of Infectious Diseases and Infection Control, Jena University Hospital, 07743 Jena, Germany.

Center for Sepsis Control and Care, Jena University Hospital, 07743 Jena, Germany.

出版信息

Vaccines (Basel). 2024 Sep 21;12(9):1080. doi: 10.3390/vaccines12091080.

Abstract

BACKGROUND

In many countries, an increase in influenza and pneumococcal vaccination rates was observed during the COVID-19 pandemic. We examined how attitude, risk perception and knowledge towards influenza and pneumococcal vaccines of at-risk patients developed when the COVID-19 pandemic subsided and if COVID-19 vaccination attitude (VA) was still associated with the attitudes towards the two other vaccines.

METHODS

We used longitudinal data from two surveys conducted in Germany in 2021 and 2023 among persons with chronic diseases. We assessed VA, risk perception, vaccination knowledge and further psychological determinants of vaccine acceptance. Structural equation modelling using full information maximum likelihood was used to estimate multivariate regressions with planned missing data.

RESULTS

Among 543 respondents, the influenza and pneumococcal vaccination rates remained relatively stable between 2021 and 2023. VA also remained unchanged at a moderately positive level, while COVID-19 VA decreased. A constantly positive association between COVID-19 VA and influenza as well as pneumococcal VA was found, independent from a general VA. The perceived danger of influenza increased between 2021 and 2023 and was among the strongest predictors of influenza VA.

CONCLUSIONS

Also at the subsiding pandemic, COVID-19 VA was constantly associated with the influenza and pneumococcal VA. It seems sensible to take these aspects into account when designing future vaccination campaigns for at-risk patients.

TRIAL REGISTRATION

DRKS00024561. Registered 9 March 2021.

摘要

背景

在许多国家,新冠疫情期间流感和肺炎球菌疫苗接种率有所上升。我们研究了在新冠疫情消退后,高危患者对流感和肺炎球菌疫苗的态度、风险认知及知识是如何变化的,以及新冠疫苗接种态度(VA)是否仍与对其他两种疫苗的态度相关。

方法

我们使用了2021年和2023年在德国对慢性病患者进行的两项调查的纵向数据。我们评估了VA、风险认知、疫苗接种知识以及疫苗接受度的其他心理决定因素。使用完全信息最大似然法的结构方程模型来估计包含计划缺失数据的多元回归。

结果

在543名受访者中,2021年至2023年期间流感和肺炎球菌疫苗接种率保持相对稳定。VA也保持在中等偏正水平不变,而新冠VA有所下降。发现新冠VA与流感以及肺炎球菌VA之间始终存在正相关,且独立于一般VA。2021年至2023年期间,对流感的感知危险增加,并且是流感VA的最强预测因素之一。

结论

即使在疫情消退阶段,新冠VA也始终与流感和肺炎球菌VA相关。在为高危患者设计未来的疫苗接种活动时考虑这些因素似乎是明智的。

试验注册

DRKS00024561。2021年3月9日注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bec/11435497/bbe1d8d63eaf/vaccines-12-01080-g001.jpg

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