Dang Yuan, Wang Lin, Liu Yuming, Wang Boyan, Deng Huiwen, Ye Can, Wang Chunping, Huang Yangmu
School of Public Health, Peking University, Beijing 100191, China.
Child Health Care Center, Children's Hospital, Capital Institute of Pediatrics, Beijing 100020, China.
Vaccines (Basel). 2024 Sep 22;12(9):1082. doi: 10.3390/vaccines12091082.
This study examines the recommendation behaviors and influencing factors for the 13-valent Pneumococcal Conjugate Vaccine (PCV13) among 3579 Chinese healthcare workers (HCWs), including 1775 pediatric care providers (Peds-PCPs) and 1804 primary care providers (PCPs). Data were collected from May to July 2023 through a national cross-sectional survey using a structured questionnaire, distributed across hospitals providing pediatric services in five provincial-level administrative divisions. The sociodemographic data, vaccine knowledge, and recommendation practices were analyzed using Pearson's chi-square test, Wilcoxson rank-sum test, and multivariate logistic regression. Results show that while PCPs are more likely to recommend PCV13, vaccine hesitancy persists among Peds-PCPs. Logistic regression revealed that higher influenza vaccination intention, salary, vaccine consultation frequency, familiarity with immunization, work ethic, and flexible schedules positively impacted HCWs' recommendation behavior. Factors influencing Peds-PCPs' recommendations include vaccine training (OR: 1.470, CI: 1.049-2.509), safety recognition (OR: 1.986, CI: 1.163-3.391), concern over rejection (OR = 1.274, CI: 1.076-1.508) and vaccine cost (OR = 1.203, CI: 1.023-1.414). For PCPs, influencing factors were the perceived susceptibility of children to pneumonia (OR = 2.185, CI: 1.074-4.445), acceptance of herd immunity (OR: 1.717, CI: 1.101-2.677), and belief that parents with better family conditions are more likely to accept vaccine recommendations (OR = 1.229, CI: 1.024-1.477). This survey underscores the need for tailored interventions to address differing perceptions and enhance confidence in the safety and efficacy of vaccines among HCWs, particularly Peds-PCPs.
本研究调查了3579名中国医护人员(HCW)中13价肺炎球菌结合疫苗(PCV13)的推荐行为及影响因素,其中包括1775名儿科护理提供者(儿科PCP)和1804名初级护理提供者(PCP)。2023年5月至7月,通过一项全国性横断面调查,使用结构化问卷收集数据,该问卷分发至五个省级行政区提供儿科服务的医院。使用Pearson卡方检验、Wilcoxon秩和检验和多因素逻辑回归分析社会人口统计学数据、疫苗知识和推荐行为。结果显示,虽然PCP更有可能推荐PCV13,但儿科PCP中疫苗犹豫现象仍然存在。逻辑回归显示,更高的流感疫苗接种意愿、薪资、疫苗咨询频率、对免疫接种的熟悉程度、职业道德和灵活的工作时间表对医护人员的推荐行为有积极影响。影响儿科PCP推荐的因素包括疫苗培训(OR:1.470,CI:1.049 - 2.509)、对安全性的认可(OR:1.986,CI:1.163 - 3.391)、对拒绝的担忧(OR = 1.274,CI:1.076 - 1.508)和疫苗成本(OR = 1.203,CI:1.023 - 1.414)。对于PCP,影响因素包括认为儿童对肺炎的易感性(OR = 2.185,CI:1.074 - 4.445)、对群体免疫的接受程度(OR:1.717,CI:1.101 - 2.677)以及认为家庭条件较好的父母更有可能接受疫苗推荐(OR = 1.229,CI:1.024 - 1.477)。这项调查强调了需要采取针对性干预措施,以解决不同的看法,并增强医护人员,特别是儿科PCP对疫苗安全性和有效性的信心。