Department of Anaesthesiology and Pain Medicine, The Catholic University of Korea, St Vincent's Hospital, Suwon, Korea.
J Int Med Res. 2024 Sep;52(9):3000605241285155. doi: 10.1177/03000605241285155.
Continuous fasciculation that occurs without weakness is referred to as benign fasciculation. Although generally considered non-threatening, cases that persist can significantly impact an individual's quality of life. This study presents a case of a male patient in his 30s experiencing unyielding twitching localized to the sole of his left foot for 2 years. His medical history was devoid of any notable neuromuscular diseases. Results from electromyography testing were also normal for all parameters. Attempts with pharmacological intervention did not yield any improvement of his condition. Although a nerve block targeting the left tibial nerve managed to reduce the severity of the twitching, it failed to decrease its frequency or provide a lasting solution. In search of a more effective treatment, botulinum toxin was administered via ultrasound guidance into the flexor hallucis and digitorum longus muscles. This approach resulted in a marked reduction in both the frequency and severity of the twitching, enabling the patient to resume his daily activities and achieve restful sleep without experiencing any adverse effects. Through this case, the efficacy of botulinum toxin injections as a treatment for intractable twitching is underscored, offering valuable insights into potential therapeutic strategies for similar clinical presentations.
持续但不伴有无力的肌束颤动称为良性肌束颤动。尽管通常被认为不具威胁性，但持续存在的病例可能会显著影响个体的生活质量。本研究介绍了一位 30 多岁男性患者的病例，他的左脚底持续出现无法控制的抽搐，已经持续了 2 年。他的病史中没有任何明显的神经肌肉疾病。肌电图测试的所有参数结果也正常。药物干预的尝试也未能改善他的病情。虽然针对左胫神经的神经阻滞成功地减轻了抽搐的严重程度，但未能降低其频率或提供持久的解决方案。为了寻找更有效的治疗方法，采用超声引导将肉毒杆菌毒素注入屈肌和趾长屈肌。这种方法显著降低了抽搐的频率和严重程度，使患者能够恢复日常活动并获得宁静的睡眠，而没有任何不良反应。通过这个病例，强调了肉毒杆菌毒素注射作为治疗难治性抽搐的有效性，为类似临床表现的潜在治疗策略提供了有价值的见解。
