老年人甲状腺检查解读：更新指南。

Geriatrics. 1985 Dec;40(12):61-8.

T4 determinations by themselves have been reported to be cost-effective as a screening test to identify patients with unsuspected thyroid disease. The most consistent finding in healthy older subjects, that of a decrease in circulating T3, means that reference intervals for T3 need to be adjusted downward by as much as 25%.

据报道，仅进行T4测定作为一种筛查试验来识别未被怀疑患有甲状腺疾病的患者具有成本效益。健康老年受试者中最一致的发现，即循环T3降低，意味着T3的参考区间需要向下调整多达25%。