Department of Obstetrics and Gynecology, Selcuk University Faculty of Medicine, Konya, Turkey.
Department of Perinatology, Selcuk University Faculty of Medicine, Konya, Turkey.
Eur J Obstet Gynecol Reprod Biol. 2024 Nov;302:254-261. doi: 10.1016/j.ejogrb.2024.09.032. Epub 2024 Sep 23.
We aimed to establish normal reference ranges for insula, sylvian fissure (SF), parieto-occipital fissure (POF), and calcarine fissure (CF) measured by prenatal ultrasonography (USG) between 20-24 weeks of gestation in healthy fetuses.
A total of 186 fetuses in the second trimester were evaluated by transabdominal USG. All measurements were obtained by a single clinician. The study was divided into four subgroups (Group A: 20-20 weeks six days, Group B: 21-21 weeks six days, Group C: 22-22 weeks six days, Group D: 23-23 weeks six days).
Eight fetuses (4.23 %) between 20 and 21 weeks of gestation could not be included in the study because the sulcus borders could not be clearly evaluated. Measurements were obtained in all fetuses over 21 weeks of gestation. Reference ranges were obtained for insula, SF, POF, and CF in all fetuses and subgroups. At 20 and 23 weeks and six days gestation, mean insula depth was 14.96 ± 1.62 mm (min 11.0 mm - max 18.9 mm), mean SF depth was 6.96 ± 1.35 mm (min 3.6 mm - max 10.0 mm), mean POF depth was 2.05 ± 0.66 mm (min 1.1 mm - max 5.6 mm) and mean CF depth was 2.42 ± 0.68 mm (min 1.5 mm - 6.1 mm). There was a correlation between the cerebellum and cisterna magna and all fissure depths.
Our nomograms of healthy fetuses may be helpful in the early detection of cortical maturation abnormalities.
旨在建立正常的参考范围，用于测量 20-24 孕周健康胎儿的岛叶、外侧裂（SF）、顶枕裂（POF）和距状裂（CF）。
对 186 例 2 期胎儿进行经腹超声检查。所有测量均由一名医生完成。研究分为 4 个亚组（A 组：20-20 周 6 天；B 组：21-21 周 6 天；C 组：22-22 周 6 天；D 组：23-23 周 6 天）。
20-21 周的 8 例（4.23%）胎儿由于无法清楚地评估脑沟边界而无法纳入研究。所有 21 周以上的胎儿都能进行测量。所有胎儿和亚组均获得了岛叶、SF、POF 和 CF 的参考范围。在 20 周和 23 周 6 天时，岛叶的平均深度为 14.96±1.62mm（最小 11.0mm-最大 18.9mm），SF 的平均深度为 6.96±1.35mm（最小 3.6mm-最大 10.0mm），POF 的平均深度为 2.05±0.66mm（最小 1.1mm-最大 5.6mm），CF 的平均深度为 2.42±0.68mm（最小 1.5mm-最大 6.1mm）。小脑和脑池与所有脑裂深度之间存在相关性。
我们的正常胎儿图谱可能有助于早期发现皮质成熟异常。
