Aly Manuel Mussa, Berti Cristiana, Chemane Felício, Macuelo Cesar, Marroda Kodak Raúl, La Vecchia Adriano, Agostoni Carlo, Baglioni Mattia
NIOP, Nucleo de Investigação Operacional de Pemba, Pemba, Cabo Delgado, Mozambique.
Pediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Eur J Clin Nutr. 2025 Jan;79(1):79-82. doi: 10.1038/s41430-024-01516-7. Epub 2024 Sep 28.
In July 2022, we conducted a pilot cross-sectional study, within a project funded by the United Nations International Children's Emergency Fund, to investigate the prevalence and predictors of anemia in children aged 6-59 months living in the Ntele camp (Mozambique), created for internally displaced persons (IDPs). We analyzed blood samples for hemoglobin (Hb) and Plasmodium antigens; stool and urine for parasites. Associations between variables were assessed by performing univariate and multivariate logistic regressions. Based on the World Health Organization's Hb cut-offs, we defined anemia (Hb < 110 g/L) as mild (Hb = 100-109 g/L), moderate (Hb = 70-99 g/L), and severe (Hb < 70 g/L). We included 245 children, 212 (83%) were anemic, with 30 (12%) being severely anemic, and 95 (39%) suffered from malaria. Children with moderate-severe anemia were younger than others (mean age = 25.3 and 29.5 months, respectively; p = 0.02). Malaria was positively correlated with moderate to severe anemia (crude OR [95%CI] = 2.5 [1.5-4.5]; sex and age-adjusted OR [95%CI] = 3.1 [1.7-5.6]). Anemia in children under 5 years of age represents an urgent public health threat in the IDPs camp of Ntele, with malaria potentially making them much more susceptible to moderate-severe anemia and other diseases.
2022年7月,我们在联合国国际儿童紧急基金资助的一个项目中开展了一项试点横断面研究,以调查生活在为境内流离失所者设立的(莫桑比克)恩特勒营地中6至59个月大儿童贫血的患病率及预测因素。我们分析了血液样本中的血红蛋白(Hb)和疟原虫抗原;分析了粪便和尿液中的寄生虫。通过进行单变量和多变量逻辑回归评估变量之间的关联。根据世界卫生组织的Hb临界值,我们将贫血(Hb < 110 g/L)定义为轻度(Hb = 100 - 109 g/L)、中度(Hb = 70 - 99 g/L)和重度(Hb < 70 g/L)。我们纳入了245名儿童,其中212名(83%)贫血,30名(12%)重度贫血,95名(39%)患有疟疾。中度至重度贫血的儿童比其他儿童年龄小(平均年龄分别为25.3个月和29.5个月;p = 0.02)。疟疾与中度至重度贫血呈正相关(粗比值比[95%置信区间]= 2.5 [1.5 - 4.5];经性别和年龄调整后的比值比[95%置信区间]= 3.1 [1.7 - 5.6])。5岁以下儿童贫血是恩特勒境内流离失所者营地中一个紧迫的公共卫生威胁,疟疾可能使他们更容易患中度至重度贫血及其他疾病。