Wu Ying-Ru, Su Wen-So, Lin Kun-Der, Lin I-Mei
Department of Psychology, College of Humanities and Social Sciences, Kaohsiung Medical University, 100, Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan.
The Lin's Clinic, Kaohsiung, 807057, Taiwan.
Appl Psychophysiol Biofeedback. 2024 Sep 29. doi: 10.1007/s10484-024-09666-x.
In type 2 diabetes mellitus (T2DM), decreased autonomic activation and heightened negative emotions may worsen glycemic control. This study investigated the effects of heart rate variability biofeedback (HRVB) on autonomic activation, negative emotions, diabetes self-care, and glycemic control in patients with T2DM. A total of 61 participants with T2DM were assigned to either the HRVB group (n = 30; 62.67 ± 7.28 years; 14 females) or the control group (n = 31; 63.39 ± 6.96 years; 14 females). Both groups received the treatment as usual, and the HRVB group received 60 min of HRVB sessions weekly for 6 weeks. Participants completed psychological questionnaires, a resting electrocardiogram (ECG), and breathing rate assessments at pre- and post-tests. Heart rate variability (HRV) indices were derived from ECG data, and glycated hemoglobin (HbA1c) levels were collected from the electronic medical records. The analysis revealed significant Group × Time interaction effects on HRV indices, breathing rate, depression symptoms, and diabetes self-care behavior. The HRVB group demonstrated higher HRV indices, lower breathing rate, and improved diabetes self-care behavior compared to the control group. Moreover, the HRVB group showed enhanced HRV indices and diabetes self-care behavior, as well as reduced breathing rate and depression in the post-test compared to the pre-test. However, there was no significant interaction effect on HbA1c levels. Six sessions of HRVB proved effective as a complementary therapy for T2DM, enhancing HRV indices, alleviating depressive symptoms, and promoting better diabetes self-care behaviors.
在2型糖尿病（T2DM）中，自主神经激活降低和负面情绪加剧可能会使血糖控制恶化。本研究调查了心率变异性生物反馈（HRVB）对T2DM患者自主神经激活、负面情绪、糖尿病自我管理和血糖控制的影响。共有61名T2DM患者被分为HRVB组（n = 30；62.67±7.28岁；14名女性）或对照组（n = 31；63.39±6.96岁；14名女性）。两组均接受常规治疗，HRVB组每周接受60分钟的HRVB治疗，共6周。参与者在测试前和测试后完成心理问卷、静息心电图（ECG）和呼吸频率评估。心率变异性（HRV）指标由ECG数据得出，糖化血红蛋白（HbA1c）水平从电子病历中收集。分析显示，组×时间交互作用对HRV指标、呼吸频率、抑郁症状和糖尿病自我管理行为有显著影响。与对照组相比，HRVB组表现出更高的HRV指标、更低的呼吸频率和改善的糖尿病自我管理行为。此外，与测试前相比，HRVB组在测试后显示出更高的HRV指标和糖尿病自我管理行为，以及更低的呼吸频率和抑郁程度。然而，对HbA1c水平没有显著的交互作用。六次HRVB治疗被证明是T2DM的一种有效辅助治疗方法，可提高HRV指标、减轻抑郁症状并促进更好的糖尿病自我管理行为。
