Department of Anesthesiology, Peking University Hospital of Stomatology, No.22, Zhongguancun South Street, Haidian District, Beijing, 100081, China.
BMC Anesthesiol. 2024 Sep 28;24(1):338. doi: 10.1186/s12871-024-02726-z.
The objective of this study was to observe the incidence and potential risk factors of postoperative depression and anxiety in patients during the early period after undergoing orthognathic surgery.
From March 7 to September 7, 2023, patients ≥ 18 years of age who were scheduled for elective orthognathic surgery under general anesthesia in Peking University School and Hospital of Stomatology were included in this study. We prospectively evaluated their degrees of pre- and postoperative depression and anxiety using the Patient Health Questionnaire-9 and the State Trait Anxiety Inventory. Associations between the perioperative factors and occurrences of postoperative anxiety and depression were evaluated using a multivariate logistic regression model.
A total of 371 patients were included in the analysis. Within five days after surgery, we observed the occurrence of depression in 32% (116) of the patients and anxiety in 72.8% (270) of them. Their preoperative depression score on the Pain Catastrophizing Scale and intraoperative urine output were significantly associated with a higher risk of postoperative depression. The presence of preoperative anxiety, postoperative moderate-to-severe pain, postoperative nausea and vomiting and postoperative insomnia were significantly associated with a higher risk of postoperative anxiety. Furthermore, a monthly income ≥ ¥10000 was found to be significantly associated with a lower risk of postoperative anxiety.
Postoperative depression and anxiety are common among patients who undergo orthognathic surgery. Moreover, preoperative psychological status and incidence of postoperative adverse events were associated with an increased risk of depression and anxiety after surgery. The results of the present study suggest that careful psychological assessment and appropriate management are necessary to improve patients' recovery following orthognathic surgery.
本研究旨在观察接受正颌手术后早期患者发生抑郁和焦虑的发生率及潜在危险因素。
2023 年 3 月 7 日至 9 月 7 日,纳入北京大学口腔医学院接受全身麻醉择期正颌手术的年龄≥18 岁的患者。使用患者健康问卷-9 项和状态特质焦虑量表前瞻性评估他们术前和术后的抑郁和焦虑程度。使用多变量逻辑回归模型评估围手术期因素与术后焦虑和抑郁发生的相关性。
共纳入 371 例患者进行分析。术后 5 天内,我们观察到 32%(116 例)的患者发生抑郁,72.8%(270 例)的患者发生焦虑。术前疼痛灾难化量表评分和术中尿量与术后抑郁风险增加显著相关。术前焦虑、术后中重度疼痛、术后恶心呕吐和术后失眠与术后焦虑风险增加显著相关。此外,月收入≥¥10000 与术后焦虑风险降低显著相关。
正颌手术后患者常发生术后抑郁和焦虑。此外,术前心理状态和术后不良事件的发生与术后抑郁和焦虑的风险增加相关。本研究结果表明,需要进行仔细的心理评估和适当的管理,以改善正颌手术后患者的恢复情况。