Shastov Alexander L, Kolchin Sergey N, Malkova Tatiana A
Bone Infection Clinic, Ilizarov National Medical Research Center for Traumatology and Orthopaedics, Kurgan 640014, Kurganskaya Oblast', Russia.
Orthopaedic Department 4, Ilizarov National Medical Research Center for Traumatology and Orthopaedics, Kurgan 640014, Kurganskaya Oblast', Russia.
World J Orthop. 2025 Jul 18;16(7):107337. doi: 10.5312/wjo.v16.i7.107337.
Management of post-traumatic long-bone defects remains relevant and challenging despite the rapid development of approaches to their treatment. Dominant positions are occupied by the Ilizarov method, bone autogenous grafting and the Masquelet induced membrane technique (IMT). The IMT is aimed at reducing extensive defect treatment duration and for this reason has gained great popularity. However, the assessment of its effectiveness is difficult due to a limited number of clinical series. The varying clinical manifestations of bone defect severity do not allow a comprehensive evaluation of IMT effectiveness. One of them is infection in the defect area. The purpose of our literature review is an analysis of studies on IMT application in infected non-infected long-bone defects of the lower extremitie published over the last 10 years. It focuses on the investigation of similarities and fundamental differences in the need for antibiotics, timing of spacer fixation, methods of collecting donor bone and fixators used for consolidation. The studies show that the IMT has been globally used in aseptic and osteomyelitic defects due to its clinical effectiveness. Authors' variations and improvements in its practical implementation indicate the ongoing development and the interest of researchers in this technique.
尽管创伤后长骨缺损的治疗方法迅速发展，但对其的管理仍然具有现实意义且颇具挑战性。伊利扎罗夫方法、自体骨移植和马斯克莱诱导膜技术（IMT）占据主导地位。IMT旨在缩短广泛缺损的治疗时间，因此广受欢迎。然而，由于临床系列数量有限，评估其有效性较为困难。骨缺损严重程度的临床表现各异，无法全面评估IMT的有效性。其中之一是缺损区域的感染。我们文献综述的目的是分析过去10年发表的关于IMT在下肢感染性和非感染性长骨缺损中应用的研究。它侧重于调查在抗生素需求、间隔器固定时机、供体骨采集方法以及用于巩固的固定器方面的异同。研究表明，由于其临床有效性，IMT已在全球范围内用于无菌性和骨髓炎缺损。作者在其实际应用中的变化和改进表明该技术仍在不断发展，且受到研究人员的关注。
