Drewitz Karl Philipp, Stark Klaus J, Zimmermann Martina E, Heid Iris M, Apfelbacher Christian J
Institute of Social Medicine and Health Systems Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
Dermatology. 2025;241(1):1-9. doi: 10.1159/000541590. Epub 2024 Sep 27.
Atopic dermatitis (AD) and psoriasis appear to affect 2-3% (lifetime prevalence) people worldwide. However, there are little epidemiological data on the prevalence of those two chronic inflammatory skin diseases in the elderly. The aim of this study was to provide frequency estimates of AD and psoriasis obtained from an elderly population in Germany.
We examined baseline data from the AugUR study, a cohort study focusing on an aging population in the city and the vicinity of Regensburg, Germany. We estimated raw frequencies of physician-diagnosed AD and psoriasis from participants' self-reports in personal interviews. These frequencies were adjusted to reflect the demographic distribution of the Bavarian population, considering both sex and age groupings spanning 5 or 10 years and reported with 95% confidence interval (CI).
Data from 1,133 participants aged 70-95 (median age 76.7 years, 45.1% women) were available for analysis. Physician-diagnosed AD was reported by 3.3% (95% CI: 2.3-4.5) of participants (2.4% from men, 4.3% from women) and 5.6% (95% CI: 4.3-7.1%) reported physician-diagnosed psoriasis (6.6% in men, 4.3% in women). Age- and sex-standardized frequency estimates for AD were 3.4% (95% CI: 2.4-4.6, 2.6% in men, 4.3% in women) and 5.3% for psoriasis (95% CI: 4.1-6.8, 6.3% in men and 4.1% in women).
This study indicates a lower than previously reported lifetime prevalence of AD (3.4% vs. 8-10%) and a higher one regarding psoriasis (5.3% vs. 2-4%) in highly aged individuals. More epidemiological research in elderly populations using validated physician diagnoses is desirable.
Atopic dermatitis (AD) and psoriasis appear to affect 2-3% (lifetime prevalence) people worldwide. However, there are little epidemiological data on the prevalence of those two chronic inflammatory skin diseases in the elderly. The aim of this study was to provide frequency estimates of AD and psoriasis obtained from an elderly population in Germany.
We examined baseline data from the AugUR study, a cohort study focusing on an aging population in the city and the vicinity of Regensburg, Germany. We estimated raw frequencies of physician-diagnosed AD and psoriasis from participants' self-reports in personal interviews. These frequencies were adjusted to reflect the demographic distribution of the Bavarian population, considering both sex and age groupings spanning 5 or 10 years and reported with 95% confidence interval (CI).
Data from 1,133 participants aged 70-95 (median age 76.7 years, 45.1% women) were available for analysis. Physician-diagnosed AD was reported by 3.3% (95% CI: 2.3-4.5) of participants (2.4% from men, 4.3% from women) and 5.6% (95% CI: 4.3-7.1%) reported physician-diagnosed psoriasis (6.6% in men, 4.3% in women). Age- and sex-standardized frequency estimates for AD were 3.4% (95% CI: 2.4-4.6, 2.6% in men, 4.3% in women) and 5.3% for psoriasis (95% CI: 4.1-6.8, 6.3% in men and 4.1% in women).
This study indicates a lower than previously reported lifetime prevalence of AD (3.4% vs. 8-10%) and a higher one regarding psoriasis (5.3% vs. 2-4%) in highly aged individuals. More epidemiological research in elderly populations using validated physician diagnoses is desirable.
特应性皮炎（AD）和银屑病似乎影响着全球2%-3%的人口（终生患病率）。然而，关于这两种慢性炎症性皮肤病在老年人中的患病率，几乎没有流行病学数据。本研究的目的是提供德国老年人群中AD和银屑病的发病率估计。
我们检查了AugUR研究的基线数据，这是一项针对德国雷根斯堡市及其周边老年人群的队列研究。我们根据参与者在个人访谈中的自我报告，估计医生诊断的AD和银屑病的原始发病率。这些发病率经过调整，以反映巴伐利亚人口的人口分布情况，同时考虑了跨越5年或10年的性别和年龄分组，并以95%置信区间（CI）报告。
共有1133名年龄在70-95岁之间（中位年龄76.7岁，45.1%为女性）的参与者的数据可供分析。3.3%（95%CI：2.3-4.5）的参与者报告有医生诊断的AD（男性为2.4%，女性为4.3%），5.6%（95%CI：4.3-7.1%）报告有医生诊断的银屑病（男性为6.6%，女性为4.3%）。AD的年龄和性别标准化发病率估计为3.4%（95%CI：2.4-4.6，男性为2.6%，女性为4.3%），银屑病为5.3%（95%CI：4.1-6.8，男性为6.3%，女性为4.1%）。
本研究表明，在高龄个体中，AD的终生患病率低于先前报告的水平（3.4%对8%-10%），而银屑病的患病率则高于先前报告的水平（5.3%对2%-4%）。需要在老年人群中开展更多使用经过验证的医生诊断的流行病学研究。
特应性皮炎（AD）和银屑病似乎影响着全球2%-3%的人口（终生患病率）。然而，关于这两种慢性炎症性皮肤病在老年人中的患病率，几乎没有流行病学数据。本研究的目的是提供德国老年人群中AD和银屑病的发病率估计。
我们检查了AugUR研究的基线数据，这是一项针对德国雷根斯堡市及其周边老年人群的队列研究。我们根据参与者在个人访谈中的自我报告，估计医生诊断的AD和银屑病的原始发病率。这些发病率经过调整，以反映巴伐利亚人口的人口分布情况，同时考虑了跨越5年或10年的性别和年龄分组，并以95%置信区间（CI）报告。
共有1133名年龄在70-95岁之间（中位年龄76.7岁，45.1%为女性）的参与者的数据可供分析。3.3%（95%CI：2.3-4.5）的参与者报告有医生诊断的AD（男性为2.4%，女性为4.3%），5.6%（95%CI：4.3-7.1%）报告有医生诊断的银屑病（男性为6.6%，女性为4.3%）。AD的年龄和性别标准化发病率估计为3.4%（95%CI：2.4-4.6，男性为2.6%，女性为4.3%），银屑病为5.3%（95%CI：4.1-6.8，男性为6.3%，女性为4.1%）。
本研究表明，在高龄个体中，AD的终生患病率低于先前报告的水平（3.4%对8%-10%），而银屑病的患病率则高于先前报告的水平（5.3%对2%-4%）。需要在老年人群中开展更多使用经过验证的医生诊断的流行病学研究。
