Das Sasmita, Behera Maheswari, Ranjan Das Smruti, Charan Behera Kanhu, Singh Lakshmi
Department of Botany, College of Basic Science and Humanities, Odisha University of Agriculture and Technology, Odisha, Bhubaneswar, 751003, India.
Department of Plant Science, School of Life Sciences, University of Hyderabad, Hyderabad, 500046, India.
Chem Biodivers. 2025 Feb;22(2):e202401695. doi: 10.1002/cbdv.202401695. Epub 2024 Nov 8.
Over the past few decades, seaweed has been explored as a sustainable source in biotechnological and biomedical industries because of its multiple biopotential actions. However, the composition of biomolecules such as carbohydrates, lipids, fatty acids, free amino acids, ash, minerals, vitamins, and especially protein in green seaweeds varies from species to species based on their growth stage and the environmental conditions. Specifically, seaweed-derived bioactive proteins and peptides have the potential for several health benefits. They serve as a balanced diet. Protein which is an extensive macronutrient in human nutrition, should be explored to avoid using animal-sourced protein, which is expensive to consume. Bioactive peptides that are isolated from marine algae consist of various kinds of functional properties. In the food industry, seaweeds are novel molecules for being used in both nutritional foods and nutraceuticals. In both in vitro and In vivo conditions, various seaweed-derived bioactive compounds have shown a broad range of biological activities including anti-cancer and immunomodulatory, anti-hypertensive, and anti-coagulant activities. Hence, this review paper discusses the screening of seaweed-derived biochemicals with a special focus on their proteins, peptide contents, and nutra-pharmaceutical values.
在过去几十年里,由于其多种生物活性作用,海藻已被探索作为生物技术和生物医学产业中的可持续资源。然而,绿藻中碳水化合物、脂质、脂肪酸、游离氨基酸、灰分、矿物质、维生素,尤其是蛋白质等生物分子的组成因物种、生长阶段和环境条件而异。具体而言,海藻衍生的生物活性蛋白质和肽具有多种健康益处。它们可作为均衡饮食。蛋白质是人类营养中的一种重要常量营养素,应探索利用海藻蛋白以避免使用消费成本高昂的动物源蛋白质。从海藻中分离出的生物活性肽具有多种功能特性。在食品工业中,海藻是用于营养食品和营养保健品的新型分子。在体外和体内条件下,各种海藻衍生的生物活性化合物都显示出广泛的生物活性,包括抗癌和免疫调节、抗高血压和抗凝血活性。因此,本文综述讨论了海藻衍生生物化学物质的筛选,特别关注其蛋白质、肽含量和营养药用价值。