Université Clermont Auvergne, CNRS, SIGMA Clermont, Institut Pascal, F-63000 Clermont-Ferrand, France.
Laboratoire de Génie Enzymatique et Microbiologie, Équipe de Biotechnologie des Algues, Département Génie Biologique, Ecole Nationale d'Ingénieurs de Sfax, Université de Sfax, Sfax 3038, Tunisie.
Molecules. 2020 Jul 9;25(14):3152. doi: 10.3390/molecules25143152.
Bioactive compounds with diverse chemical structures play a significant role in disease prevention and maintenance of physiological functions. Due to the increase in industrial demand for new biosourced molecules, several types of biomasses are being exploited for the identification of bioactive metabolites and techno-functional biomolecules that are suitable for the subsequent uses in cosmetic, food and pharmaceutical fields. Among the various biomasses available, macroalgae are gaining popularity because of their potential nutraceutical and health benefits. Such health effects are delivered by specific diterpenes, pigments (fucoxanthin, phycocyanin, and carotenoids), bioactive peptides and polysaccharides. Abundant and recent studies have identified valuable biological activities of native algae polysaccharides, but also of their derivatives, including oligosaccharides and (bio)chemically modified polysaccharides. However, only a few of them can be industrially developed and open up new markets of active molecules, extracts or ingredients. In this respect, the health and nutraceutical claims associated with marine algal bioactive polysaccharides are summarized and comprehensively discussed in this review.
具有多样化学结构的生物活性化合物在疾病预防和生理功能维持方面发挥着重要作用。由于工业界对新型生物源分子的需求不断增加,人们正在利用多种生物质来鉴定具有生物活性的代谢物和技术功能生物分子,这些物质适合随后在化妆品、食品和制药领域使用。在现有的各种生物质中,海藻因其具有潜在的营养和健康益处而受到关注。这些健康效应是由特定的二萜、色素(岩藻黄素、藻蓝蛋白和类胡萝卜素)、生物活性肽和多糖提供的。丰富且最新的研究已经确定了天然藻类多糖及其衍生物(寡糖和(生物)化学修饰多糖)的有价值的生物学活性。然而,只有少数能够进行工业化开发并开拓新的活性分子、提取物或成分市场。在这方面,本文总结并全面讨论了与海洋藻类生物活性多糖相关的健康和营养声称。