Smith C I, Hammarström L, Palmblad J
J Clin Lab Immunol. 1985 Aug;17(4):191-5.
A male with common variable hypogammaglobulinemia had subnormal but detectable IgA levels (0.2-0.4 g/l). During a period of 1 yr his serum IgA decreased below the detection level to less than 1/10(5) of the original concentration. Serum IgG and IgM were both low but remained constant during the follow-up time. In serum samples lacking IgA, anti-IgA antibodies of the IgG1 subclass were found. His B lymphocytes had a low but detectable capacity to secrete IgA in coculture experiments with purified T cells from healthy donors.
一名患有常见变异型低丙种球蛋白血症的男性，其IgA水平低于正常但可检测到（0.2 - 0.4 g/l）。在1年的时间里，他的血清IgA降至检测水平以下，降至原浓度的1/10(5)以下。血清IgG和IgM均较低，但在随访期间保持稳定。在缺乏IgA的血清样本中，发现了IgG1亚类的抗IgA抗体。在与健康供体的纯化T细胞共培养实验中，他的B淋巴细胞分泌IgA的能力较低但可检测到。
