Huang Yan-Bing, Lin Li, Li Xin-Yu, Chen Bo-Zhu, Yuan Lu, Zheng Hui
The Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
NPJ Digit Med. 2024 Sep 29;7(1):262. doi: 10.1038/s41746-024-01264-9.
Cognitive behavioral therapy (CBT) is effective for headache disorders. However, it is unclear whether the emerging digital CBT is noninferior to face-to-face CBT. An indirect treatment comparison (ITC) meta-analysis was conducted to assess the relative effects between them using standard mean differences (SMDs). Effective sample size (ESS) and required sample size (RSS) were calculated to demonstrate the robustness of the results. Our study found that digital CBT had a similar effect on headache frequency reduction (SMD, 0.12; 95%CI, -2.45 to 2.63) compared with face-to-face CBT. The ESS had 84 participants, while the RSS had 466 participants to achieve the same power as a non-inferior head-to-head trial. Digital CBT is as effective as face-to-face CBT in preventing headache disorders. Due to the heterogeneity (I = 94.5%, τ = 1.83) and the fact that most of the included studies were on migraine prevention, further head-to-head trials are warranted.
认知行为疗法（CBT）对头痛疾病有效。然而，尚不清楚新兴的数字认知行为疗法是否不劣于面对面的认知行为疗法。进行了一项间接治疗比较（ITC）荟萃分析，以使用标准化均值差（SMD）评估它们之间的相对效果。计算了有效样本量（ESS）和所需样本量（RSS）以证明结果的稳健性。我们的研究发现，与面对面的认知行为疗法相比，数字认知行为疗法在降低头痛频率方面具有相似的效果（SMD，0.12；95%CI，-2.45至2.63）。有效样本量有84名参与者，而所需样本量有466名参与者才能达到与非劣效性头对头试验相同的效能。数字认知行为疗法在预防头痛疾病方面与面对面的认知行为疗法同样有效。由于存在异质性（I = 94.5%，τ = 1.83）且纳入的大多数研究是关于偏头痛预防的，因此有必要进行进一步的头对头试验。
