de Vries E G, Kreumer W M, Schippers D L, Mulder N H
Med Oncol Tumor Pharmacother. 1985;2(3):219-24. doi: 10.1007/BF02934551.
As many chemotherapeutic agents affect the alimentary tract the use of hyperalimentation with tube feeding during and after chemotherapy has been limited. However, patients do tolerate tube feeding well despite chemotherapy. The feeding has to be administered as continuous drip infusion and in case of bone marrow depression sterile feeding is necessary. Enteral nutrition is more physiologic, safer, easier and less expensive than parenteral nutrition. With enteral hyperalimentation the nutritional needs can be fulfilled to a large extent. Much research will be necessary to investigate the effect of enteral (hyper)alimentation on tumor metabolism and clinical effect of chemotherapy.
由于许多化疗药物会影响消化道,化疗期间及化疗后通过管饲进行胃肠外营养的应用受到限制。然而,尽管进行了化疗,患者对管饲的耐受性良好。喂食必须以连续滴注的方式进行,在骨髓抑制的情况下,无菌喂食是必要的。肠内营养比胃肠外营养更符合生理、更安全、更简便且成本更低。通过肠内胃肠外营养,营养需求在很大程度上可以得到满足。需要进行大量研究来调查肠内(胃肠外)营养对肿瘤代谢的影响以及化疗的临床效果。