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骨盆骨肉瘤手术决策的象形指南。

A pictographic guide for decision making in surgery for pelvic bone sarcoma.

作者信息

Rajasekaran Raja Bhaskara, Kurisunkal Vineet, Stevenson Jonathan D, Parry Michael C, Morris Guy V, Jeys Lee M

机构信息

Department of Musculoskeletal Oncology, Ganga Medical Centre & Hospitals Pvt. Ltd, 313, Mettupalayam Road, Coimbatore, India.

Royal Orthopaedic Hospital, Birmingham, B31 2AP, United Kingdom.

出版信息

J Orthop. 2024 Sep 3;60:71-77. doi: 10.1016/j.jor.2024.09.003. eCollection 2025 Feb.

Abstract

Pelvic bone sarcoma surgery is challenging due to complex anatomy, proximity to major neurovascular structures, and, more importantly, the potential for complications. Decision-making is vital in offering patients the best oncological and functional outcomes after surgery. Multidisciplinary teams involved from the stage of diagnosis and treatment planning, followed by surgery by experienced teams have proven to be beneficial. Tumour-free margin clearance is essential, and surgical planning must be tailored to achieve the same. The choice of reconstruction needs to be decided based on the amount of bone resected and the available expertise and resources. Lesions isolated only to PI or PIII region may not need reconstruction. Though pedestal cups and Custom-made prosthesis are useful in reconstruction after periacetabular tumour resections, hip transposition surgery is also widely practiced by surgeons with favourable outcomes particularly after neo-adjuvant radiotherapy/proton beam therapy. Navigation has shown promise in achieving tumour-negative margins and disease-free progression particularly in chondrosarcoma. A flap-based approach can be considered for hindquarter amputations; however, patients need to be counseled regarding the complications following this surgery. This article, with proposed flowcharts, is aimed at providing practicing surgeons with a guide toward decision-making while planning pelvic bone sarcoma surgery.

摘要

骨盆骨肉瘤手术具有挑战性,这是因为其解剖结构复杂、靠近主要神经血管结构,更重要的是存在发生并发症的可能性。在为患者提供术后最佳肿瘤学和功能结果方面,决策至关重要。从诊断和治疗规划阶段就参与其中的多学科团队,随后由经验丰富的团队进行手术,已被证明是有益的。实现无瘤边缘清除至关重要,手术规划必须据此进行量身定制。重建方式的选择需要根据切除的骨量以及现有的专业知识和资源来决定。仅局限于PI或PIII区域的病变可能不需要重建。虽然基座杯和定制假体在髋臼周围肿瘤切除术后的重建中很有用,但髋关节转位手术也被外科医生广泛应用,尤其在新辅助放疗/质子束治疗后取得了良好效果。导航技术在实现肿瘤阴性边缘和无病进展方面已显示出前景,特别是在软骨肉瘤中。对于后躯截肢可考虑采用皮瓣法;然而,需要向患者咨询该手术后的并发症情况。本文并附上建议的流程图,旨在为实施骨盆骨肉瘤手术的外科医生在制定手术规划时提供决策指导。

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