Salgotra Manjula, Bharti Nancy, Sinha Varsha, Tiwari Rahul, Tiwari Heena Dixit, Shashank Chapala, Kalsi Jasmine, Pujari Priyanka R
Department of Health and Medical Education, SDH Basholi, Jammu and Kashmir, India.
Department of Gynaecology, Government Medical College and Hospital, Kathua, Jammu and Kashmir, India.
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2767-S2769. doi: 10.4103/jpbs.jpbs_233_24. Epub 2024 Jul 31.
Although PCOS affects reproductive health, its consequences on the outcome of pregnancies are still up for discussion. Comparing the pregnancy outcomes of women with PCOS to a control group was the goal of this retrospective research.
Analysis of data from tertiary care centers between 2017 and 2022 was done in retrospective. While the controls ( = 300) matched for age, BMI, and parity, the PCOS group ( = 300) satisfied Rotterdam criteria. Maternal-fetal health, birth outcomes, and gestational problems were evaluated.
Compared to controls, women with PCOS had a greater incidence of preeclampsia (12.3% vs. 8.1%, = 0.023) and gestational diabetes (18.7% vs. 9.8%, < 0.001). On the other hand, there were no notable variations in low birth weight ( = 0.589) or preterm delivery ( = 0.321).
In summary, the correlation between PCOS and increased risks of gestational diabetes and preeclampsia emphasizes the necessity of customized therapies. The intricacy of PCOS's influence on birth outcomes is shown by the inconclusive results regarding preterm delivery and low birth weight, which call for more research to enhance mother and newborn health in this group.
尽管多囊卵巢综合征（PCOS）会影响生殖健康，但其对妊娠结局的影响仍有待探讨。本项回顾性研究的目的是比较患有PCOS的女性与对照组的妊娠结局。
对2017年至2022年间三级护理中心的数据进行回顾性分析。对照组（n = 300）在年龄、体重指数和产次方面匹配，PCOS组（n = 300）符合鹿特丹标准。评估母婴健康、出生结局和妊娠问题。
与对照组相比，患有PCOS的女性子痫前期（12.3%对8.1%，P = 0.023）和妊娠期糖尿病（18.7%对9.8%，P < 0.001）的发生率更高。另一方面，低出生体重（P = 0.589）或早产（P = 0.321）没有显著差异。
总之，PCOS与妊娠期糖尿病和子痫前期风险增加之间的相关性强调了个性化治疗的必要性。关于早产和低出生体重的不确定结果表明了PCOS对出生结局影响的复杂性，这需要更多研究来改善该群体中母婴的健康状况。
