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基于补充和替代医学方法治疗少弱畸精子症患者及其对辅助生殖技术结局影响的病例研究

A Case Study Based on a Complementary and Alternative Medicine Approach on an Oligoasthenoteratozoospermic Patient and its Effect on Assisted Reproductive Technology Outcome.

作者信息

Patil Rupali, Jadhao Ritesh, Anjankar Namrata, More Akash, Gajabe Gauri, Shrivastava Jarul

机构信息

Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Sawangi Meghe, Wardha, Maharashtra, India.

Clinical Embryology, Acharya Vinoba Bhave Rural Hospital, Datta Meghe Institute of Higher Education and Research, Sawangi Meghe, Wardha, Maharashtra, India.

出版信息

J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2991-S2994. doi: 10.4103/jpbs.jpbs_182_24. Epub 2024 May 29.

DOI:10.4103/jpbs.jpbs_182_24
PMID:39346324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11426558/
Abstract

A couple visited the IVF clinic to seek treatment for primary infertility. A 45-year-old quadragenarian female and her 49-year-old male partner were recommended infertility treatment after 2 years of unsuccessful attempts to conceive. The woman had a recent history of dengue and chickenpox. The male partner was advised to do a semen analysis. The report showed asthenoteratozoospermia and the semen sample viscous. On the other hand, the female was diagnosed with hypothyroidism. The male patient was given a 3-month medication treatment that included probiotic supplements and cranberry juice to treat bacterial infections and urinary tract infections. The male partner also advised medication, and regular semen analysis was performed after every 3 months. The treatment plan included intrauterine insemination (IUI), which increased the possibility of pregnancy. Fourteen days following the IUI and pregnancy test, the outcomes were positive. The case illustrates the difficulties in treating primary infertility by combining reproductive procedures, medication, and lifestyle modifications. Regularly monitoring semen quality and hormonal levels is crucial in assessing treatment success. The positive outcome of IUI suggests the effectiveness of the fertility treatment plan.

摘要

一对夫妇前往体外受精诊所寻求原发性不孕症的治疗。一名45岁的中年女性及其49岁的男性伴侣在尝试受孕2年未成功后,被建议接受不孕症治疗。该女子近期有登革热和水痘病史。男性伴侣被建议进行精液分析。报告显示为弱畸精子症且精液样本黏稠。另一方面,该女性被诊断为甲状腺功能减退。男性患者接受了为期3个月的药物治疗,包括益生菌补充剂和蔓越莓汁,以治疗细菌感染和尿路感染。男性伴侣也接受了药物治疗,每3个月进行一次常规精液分析。治疗方案包括宫内人工授精(IUI),这增加了怀孕的可能性。宫内人工授精和妊娠试验14天后,结果呈阳性。该病例说明了通过结合生殖程序、药物治疗和生活方式改变来治疗原发性不孕症的困难。定期监测精液质量和激素水平对于评估治疗成功至关重要。宫内人工授精的阳性结果表明了生育治疗方案的有效性。

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本文引用的文献

1
Predictive factors for intrauterine insemination outcomes: a review.宫腔内人工授精结局的预测因素:综述
Fertil Res Pract. 2020 Dec 11;6(1):23. doi: 10.1186/s40738-020-00092-1.
2
Treating male partners of women with bacterial vaginosis (StepUp): a protocol for a randomised controlled trial to assess the clinical effectiveness of male partner treatment for reducing the risk of BV recurrence.治疗细菌性阴道病女性的男性伴侣(StepUp):一项随机对照试验方案,旨在评估男性伴侣治疗降低 BV 复发风险的临床效果。
BMC Infect Dis. 2020 Nov 11;20(1):834. doi: 10.1186/s12879-020-05563-w.
3
Follicle-stimulating Hormone (FSH) Action on Spermatogenesis: A Focus on Physiological and Therapeutic Roles.
促卵泡激素(FSH)对精子发生的作用:聚焦生理和治疗作用
J Clin Med. 2020 Apr 3;9(4):1014. doi: 10.3390/jcm9041014.
4
The Contribution of Complementary and Alternative Medicine to Reduce Antibiotic Use: A Narrative Review of Health Concepts, Prevention, and Treatment Strategies.补充和替代医学在减少抗生素使用方面的作用:关于健康观念、预防和治疗策略的叙述性综述
Evid Based Complement Alternat Med. 2019 Feb 3;2019:5365608. doi: 10.1155/2019/5365608. eCollection 2019.
5
Evidence for the use of complementary and alternative medicines during fertility treatment: a scoping review.生育治疗中补充和替代医学的应用证据:范围综述。
BMC Complement Altern Med. 2018 May 15;18(1):158. doi: 10.1186/s12906-018-2224-7.
6
Complementary and alternative medicine use in infertility: cultural and religious influences in a multicultural Canadian setting.辅助和替代医学在不孕症中的应用:多元文化加拿大背景下的文化和宗教影响
J Altern Complement Med. 2014 Sep;20(9):686-92. doi: 10.1089/acm.2013.0329. Epub 2014 Aug 15.
7
A case of oligoasthenoteratozoospermia with AZFc deletion and persistent oxidative stress.一例伴有AZFc缺失和持续性氧化应激的少弱畸精子症病例。
Indian J Hum Genet. 2012 Sep;18(3):359-62. doi: 10.4103/0971-6866.108037.