Baars Erik W, Zoen Eefje Belt-van, Breitkreuz Thomas, Martin David, Matthes Harald, von Schoen-Angerer Tido, Soldner Georg, Vagedes Jan, van Wietmarschen Herman, Patijn Olga, Willcox Merlin, von Flotow Paschen, Teut Michael, von Ammon Klaus, Thangavelu Madan, Wolf Ursula, Hummelsberger Josef, Nicolai Ton, Hartemann Philippe, Szőke Henrik, McIntyre Michael, van der Werf Esther T, Huber Roman
Louis Bolk Institute, Kosterijland 3-5, 3981 AJ Bunnik, Netherlands.
University of Applied Sciences Leiden, Faculty of Healthcare, Zernikedreef 11, 2333 CK Leiden, Netherlands.
Evid Based Complement Alternat Med. 2019 Feb 3;2019:5365608. doi: 10.1155/2019/5365608. eCollection 2019.
The aim of this narrative review was to explore the potential contributions of CAM to reduce antibiotic use.
We searched PubMed, Embase, and Cochrane Database of Systematic Reviews with a specific, limited set of search terms and collected input from a group of expert CAM researchers to answer the question: What is known about the contribution of CAM health and health promotion concepts, infection prevention, and infection treatment strategies to reduce antibiotic use? The worldview-related CAM health concepts enable health promotion oriented infection prevention and treatment aimed at strengthening or supporting the self-regulating ability of the human organism to cope with diseases. There is some evidence that the CAM concepts of health (promotion) are in agreement with current conceptualization of health and that doctors who practice both CAM and conventional medicine prescribe less antibiotics, although selection bias of the presented studies cannot be ruled out. There is some evidence that prevention and some treatment strategies are effective and safe. Many CAM treatment strategies are promising but overall lack high quality evidence.
CAM prevention and treatment strategies may contribute to reducing antibiotic use, but more rigorous research is necessary to provide high quality evidence of (cost-)effectiveness.
本叙述性综述的目的是探讨补充替代医学（CAM）在减少抗生素使用方面的潜在作用。
我们使用一组特定的、有限的检索词在PubMed、Embase和Cochrane系统评价数据库中进行检索，并收集了一组补充替代医学专家研究人员的意见，以回答以下问题：关于补充替代医学的健康与健康促进概念、感染预防及感染治疗策略在减少抗生素使用方面的作用，我们了解哪些内容？与世界观相关的补充替代医学健康概念能够实现以健康促进为导向的感染预防和治疗，旨在增强或支持人体应对疾病的自我调节能力。有证据表明，补充替代医学的（健康）促进概念与当前的健康概念相符，并且同时从事补充替代医学和传统医学的医生开具的抗生素较少，尽管不能排除所呈现研究中的选择偏倚。有证据表明一些预防和治疗策略是有效且安全的。许多补充替代医学治疗策略很有前景，但总体上缺乏高质量证据。
补充替代医学的预防和治疗策略可能有助于减少抗生素使用，但需要更严格的研究来提供（成本）效益的高质量证据。
