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微血管减压术:多次治疗失败后对由基底动脉迂曲扩张引起的三叉神经痛的一种有效治疗方法

Microvascular Decompression: An Effective Approach for Trigeminal Neuralgia Caused by a Dolichoectatic Basilar Artery after Multiple Treatment Failures.

作者信息

Chelmis Filippos, Pakataridis Paraskevas, Sorotou Iliana, Tzineris Anastasios, Ranguelov Christo

机构信息

Faculty of Medicine, Sofia University "St. Kliment Ohridski," Sofia, Bulgaria.

Department of Neurosurgery, University Hospital Sofiamed, Sofia, Bulgaria.

出版信息

J Neurol Surg Rep. 2024 Sep 27;85(3):e156-e160. doi: 10.1055/a-2342-4086. eCollection 2024 Jul.

Abstract

Trigeminal neuralgia (TN), characterized by recurrent episodes of intense facial pain, poses diagnostic and therapeutic challenges. TN can be triggered by many factors, with rare cases (< 0.05% of the general population) associated with vertebrobasilar dolichoectasia (VBD). Our study analyzes a 74-year-old male patient with 10 years of constant unbearable left-sided facial pain, unresponsive to medications and multiple glycerol rhizotomies, performed in other centers which prompted the patient to seek care at our clinic. The confirmation of left-sided VBD by magnetic resonance imaging, computed tomography angiography, and the patient's overall satisfactory health status favored open surgery with microvascular decompression (MVD). We performed a retrosigmoid suboccipital craniotomy to reach the cerebellopontine angle, ensuring that it is the dolichoectatic basilar artery applying compression to the trigeminal nerve. We inserted a shredded Teflon implant into the trigeminal cistern following its opening. Care was exercised to ensure that there were no remaining factors causing compression. Postoperatively, pain relief was achieved, sustained at an 8-month follow-up. Treating TN arising from VBD can be difficult. The patient's overall health status and assessment play a key role in determining the appropriate course of treatment. Opting for MVD is the optimal and most effective choice, regardless of age, according to the recent literature. In cases where surgery is not feasible, the treatment options will involve medications and less invasive therapeutic approaches such as peripheral rhizotomies or stereotactic radiosurgery. Our case highlights the efficacy of MVD in addressing TN associated with VBD, underscoring the need for advanced treatment modalities and expertise in managing complex cases.

摘要

三叉神经痛(TN)以反复发作的剧烈面部疼痛为特征,带来了诊断和治疗方面的挑战。TN可由多种因素引发,极少数病例(占普通人群的<0.05%)与椎基底动脉延长扩张症(VBD)相关。我们的研究分析了一名74岁男性患者,他左侧面部持续剧痛10年,药物治疗和在其他中心进行的多次甘油神经根切断术均无效,这促使他到我们诊所寻求治疗。磁共振成像、计算机断层血管造影证实了左侧VBD,且患者整体健康状况良好,这有利于采用微血管减压术(MVD)进行开放性手术。我们进行了乙状窦后枕下开颅术以到达桥小脑角,确定是延长扩张的基底动脉对三叉神经施加压迫。打开三叉神经池后,我们将一片聚四氟乙烯植入物插入其中。术中小心操作以确保不存在残留的压迫因素。术后疼痛缓解,在8个月的随访中持续保持。治疗由VBD引起的TN可能很困难。患者的整体健康状况和评估在确定合适的治疗方案中起关键作用。根据最近的文献,无论年龄如何,选择MVD都是最佳且最有效的选择。在手术不可行的情况下,治疗选择将包括药物治疗以及侵入性较小的治疗方法,如周围神经根切断术或立体定向放射外科手术。我们报告的病例突出了MVD在治疗与VBD相关的TN方面的疗效,强调了在处理复杂病例时采用先进治疗方式和专业知识的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33ca/11436387/c88bc90304f2/10-1055-a-2342-4086-i24feb0012-1.jpg

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