Ning Chunhui, Yan Yunzi, Wang Yansong, Li Rui, Liu Wenjie, Qiu Linjie, Sun Lingyun, Yang Yufei
Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Graduate College, Beijing University of Traditional Chinese Medicine, Beijing, China.
Front Pharmacol. 2024 Sep 13;15:1369442. doi: 10.3389/fphar.2024.1369442. eCollection 2024.
CINV is a frequent adverse response to cancer treatment. There is still much to learn about the pathophysiology and initiating event of CINV, which necessitates continued research despite decades of effort. Identifying the current foci of the complex disease and assessing the scientific impact of pertinent study are made more difficult by the abundance of publications on CINV. Therefore, our goals in this article are to evaluate developments in this field, examine patterns in research domains, and gauge the expansion of CINV research production globally.
Articles about CINV published between 2012 and 2022 were found by searching the Web of Science Core Collection of Clarivate Analytics. The number of publications over time was visualized using Microsoft Office Excel 2019. CiteSpace and VOSviewer were utilized to create knowledge maps that analyzed collaborations between nations, organizations, and writers. They also presented the history of CINV research and highlighted its current areas of focus.
In this study, 846 papers in all were assessed. Most publications (237, 28.01%) came from the United States. University of Toronto was the most productive institution (34, 4.01%). With 25 articles published, or 2.96% of the total, Aapro Matti published the most. The most frequently published journal was found to be Supportive Care (158, 18.68%). "Palonosetron," "Moderately emetogenic chemotherapy," "5-HT3 receptor antagonist," and "Neurokinin 1 receptor antagonists" were considered the hot topics. It can be seen that the research focus is on the drug treatment of chemotherapy-induced nausea and vomiting.
Through bibliometric analysis, we were able to gain profound insights into CINV research for the first time. Researchers looking to uncover research frontiers and comprehend important information in this discipline may find the study's findings useful.
化疗引起的恶心呕吐(CINV)是癌症治疗常见的不良反应。尽管经过数十年努力,但关于CINV的病理生理学和起始事件仍有许多有待了解之处,这使得持续开展研究很有必要。关于CINV的大量出版物使得确定这种复杂疾病当前的研究重点以及评估相关研究的科学影响变得更加困难。因此,本文的目的是评估该领域的发展情况,审视研究领域的模式,并衡量全球CINV研究成果的扩展情况。
通过检索科睿唯安的Web of Science核心合集,查找2012年至2022年间发表的关于CINV的文章。使用Microsoft Office Excel 2019直观呈现随时间推移的出版物数量。利用CiteSpace和VOSviewer创建知识图谱,分析国家、组织和作者之间的合作情况。它们还展示了CINV研究的历史,并突出了其当前的重点领域。
本研究共评估了846篇论文。大多数出版物(237篇,占28.01%)来自美国。多伦多大学是产出最多的机构(34篇,占4.01%)。Aapro Matti发表的文章最多,有25篇,占总数的2.96%。发现发表频率最高的期刊是《支持性护理》(158篇,占18.68%)。“帕洛诺司琼”“中度致吐性化疗”“5-羟色胺3受体拮抗剂”和“神经激肽1受体拮抗剂”被视为热门话题。可以看出,研究重点在于化疗引起的恶心和呕吐的药物治疗。
通过文献计量分析,我们首次对CINV研究有了深刻认识。希望发现该学科研究前沿并理解重要信息的研究人员可能会觉得该研究结果有用。