Qureshi Moaz, Abraham Prakash A, Al-Faras Abdullah, Bamasood Omar M, Matar Kamal M
Department of Internal Medicine Adan Hospital Ministry of Health, Kuwait City, Kuwait.
Department of Anesthesia Adan Hospital Ministry of Health, Kuwait City, Kuwait.
Case Rep Neurol Med. 2024 Sep 21;2024:1234738. doi: 10.1155/2024/1234738. eCollection 2024.
Epilepsy is a common disorder caused by a myriad of drugs, of that levetiracetam is being commonly used late because of its strong safety profile and efficacy. With the increasing usage of drugs, some rare side effects may sometimes appear that can escape the most stringent checks, possibly due to the rarity of their occurrence. Rhabdomyolysis is known to occur in some patients owing to a variety of causes, even leading to kidney injury. When a drug has a side effect that is not well recognized in the literature, especially when the side effect can mimic an adverse effect of an uncommon primary illness, identifying the causal factor can be doubly difficult. To date, only limited studies have been published suggesting rhabdomyolysis linked to levetiracetam use. We report the first case of levetiracetam-induced rhabdomyolysis in Kuwait.
癫痫是一种由多种药物引起的常见疾病，其中左乙拉西坦因其强大的安全性和有效性而被广泛使用。随着药物使用的增加，有时可能会出现一些罕见的副作用，这些副作用可能会逃过最严格的检查，这可能是由于它们发生的罕见性。已知横纹肌溶解症会在一些患者中由于多种原因发生，甚至会导致肾损伤。当一种药物有一种在文献中未得到充分认识的副作用时，尤其是当这种副作用可以模仿一种罕见原发性疾病的不良反应时，确定因果因素可能会加倍困难。迄今为止，仅有有限的研究发表表明横纹肌溶解症与左乙拉西坦的使用有关。我们报告了科威特首例左乙拉西坦诱发的横纹肌溶解症病例。
