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《血泪:血汗症的罕见病例》

Crimson Tears: A Rare Case of Hematohidrosis.

作者信息

Cherukuru Sreeja, Uppara Shivarama Krishna, Raval Rutvik, Chappidi Mamatha, K Dileep Satya

机构信息

Psychiatry, Sri Venkateswara Medical College, Tirupati, IND.

Pediatrics, Sri Venkateswara Medical College, Tirupati, IND.

出版信息

Cureus. 2024 Aug 30;16(8):e68233. doi: 10.7759/cureus.68233. eCollection 2024 Aug.

DOI:10.7759/cureus.68233
PMID:39347273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11439452/
Abstract

Hematohidrosis is a rare clinical disorder characterized by oozing blood from intact skin and mucous membranes in the absence of a bleeding disorder. Most of the cases reported are from Asia. Although etiopathogenesis is unclear, it has been strongly linked to psychological stress. A nine-year-old girl was brought to the hospital with multiple episodes of painless bleeding from her nose and mouth for four days and eyes for three days, lasting four to five minutes each. Her symptoms and a thorough but unrevealing workup, including brain imaging, led to a clinical diagnosis of hematohidrosis, with parental disharmony as the underlying stress factor. Family therapy was recommended, and parent management training regarding the positive and negative reinforcement techniques was given. A significant improvement was observed at her one-month follow-up. This case adds to the current limited literature on hematohidrosis, highlighting its association with psychological stress and the importance of a multidisciplinary approach to management. Future research is warranted to elucidate molecular pathways involved in stress-induced vascular dysfunction and explore targeted therapeutic interventions.

摘要

血汗症是一种罕见的临床病症,其特征是在没有出血性疾病的情况下,完整的皮肤和黏膜渗血。报告的大多数病例来自亚洲。尽管发病机制尚不清楚,但它与心理压力密切相关。一名九岁女孩因鼻、口反复无痛出血四天,眼睛出血三天,每次持续四到五分钟,被送往医院。她的症状以及包括脑部成像在内的全面但无结果的检查,导致临床诊断为血汗症,父母关系不和谐是潜在的压力因素。建议进行家庭治疗,并给予父母关于正负强化技术的管理培训。在她一个月的随访中观察到显著改善。该病例补充了目前关于血汗症的有限文献,突出了其与心理压力的关联以及多学科管理方法的重要性。有必要进行未来研究以阐明压力诱导的血管功能障碍所涉及的分子途径,并探索有针对性的治疗干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f74/11439452/f0b9233fc2bd/cureus-0016-00000068233-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f74/11439452/99cfc93d2e0b/cureus-0016-00000068233-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f74/11439452/f0b9233fc2bd/cureus-0016-00000068233-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f74/11439452/99cfc93d2e0b/cureus-0016-00000068233-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f74/11439452/f0b9233fc2bd/cureus-0016-00000068233-i02.jpg

相似文献

1
Crimson Tears: A Rare Case of Hematohidrosis.《血泪:血汗症的罕见病例》
Cureus. 2024 Aug 30;16(8):e68233. doi: 10.7759/cureus.68233. eCollection 2024 Aug.
2
A Strange Occurrence of Hematohidrosis: A Case Report From Saudi Arabia.血汗症的罕见病例:来自沙特阿拉伯的一份病例报告。
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Case Report and Review of the Pathophysiology and Therapeutics of Adult Hematohidrosis.成人血汗症的病例报告、病理生理学及治疗方法综述
Cureus. 2023 Mar 15;15(3):e36187. doi: 10.7759/cureus.36187. eCollection 2023 Mar.
4
Blood otorrhea: blood stained sweaty ear discharges: hematohidrosis; four case series (2001-2013).血性耳漏:血染性耳汗溢液:血汗症;4例病例系列报道(2001 - 2013年)
Am J Otolaryngol. 2014 Mar-Apr;35(2):271-3. doi: 10.1016/j.amjoto.2013.09.006. Epub 2013 Sep 28.
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Hematohidrosis in Pediatric Practice - a Case Report and Review of the Literature.儿科实践中的血汗症——病例报告及文献综述
Acta Med Litu. 2024;31(1):12-21. doi: 10.15388/Amed.2024.31.1.2. Epub 2024 Feb 27.
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A case series of hematohidrosis: A puzzling medical phenomenon.血汗症病例系列:一种令人困惑的医学现象。
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Child who presented with hematohidrosis (sweating blood) with oppositional defiant disorder.出现血汗(汗血)并伴有对立违抗性障碍的儿童。
Indian J Psychiatry. 2014 Jul;56(3):289-91. doi: 10.4103/0019-5545.140649.
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An Interesting Case Report of Hematohidrosis.血汗症的一则有趣病例报告。
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Child Who Presented with Facial Hematohidrosis Compared with Published Cases.与已发表病例相比,出现面部血汗症的儿童。
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The story of a girl with weeping blood: Childhood depression with a rare presentation.一个女孩血泪交织的故事:以罕见形式呈现的儿童期抑郁症。
Indian J Psychiatry. 2015 Jan-Mar;57(1):88-90. doi: 10.4103/0019-5545.148533.

本文引用的文献

1
Hematohidrosis in Pediatric Practice - a Case Report and Review of the Literature.儿科实践中的血汗症——病例报告及文献综述
Acta Med Litu. 2024;31(1):12-21. doi: 10.15388/Amed.2024.31.1.2. Epub 2024 Feb 27.
2
A case of hematohidrosis successfully treated with a beta-blocker.1例使用β受体阻滞剂成功治疗的血汗症病例。
Clin Case Rep. 2023 May 28;11(6):e7337. doi: 10.1002/ccr3.7337. eCollection 2023 Jun.
3
Hematohidrosis, Hemolacria, and "Trichorrhage": A Systematic Review.血汗症、血性泪液及“毛发出血”:一项系统评价
Skin Appendage Disord. 2022 May;8(3):179-185. doi: 10.1159/000520648. Epub 2022 Jan 3.
4
A Strange Occurrence of Hematohidrosis: A Case Report From Saudi Arabia.血汗症的罕见病例:来自沙特阿拉伯的一份病例报告。
Cureus. 2022 Jan 28;14(1):e21682. doi: 10.7759/cureus.21682. eCollection 2022 Jan.
5
Pediatric hematidrosis - A case report and review of the literature and pathogenesis.小儿汗血症——病例报告及文献复习和发病机制探讨。
Pediatr Dermatol. 2021 Sep;38(5):994-1003. doi: 10.1111/pde.14792. Epub 2021 Sep 13.
6
Hematohidrosis of the mid-face and hands treated with oral oxybutynin.面部中部和手部汗血症经口服奥昔布宁治疗。
Pediatr Dermatol. 2021 Jul;38(4):962-963. doi: 10.1111/pde.14621. Epub 2021 May 26.
7
Bleeding from the oral cavity: a new case of hematohidrosis.口腔出血:血汗症一例新病例。
Int J Dermatol. 2020 Nov;59(11):e421-e422. doi: 10.1111/ijd.15021. Epub 2020 Jun 23.
8
A case series of hematohidrosis: A puzzling medical phenomenon.血汗症病例系列:一种令人困惑的医学现象。
Turk J Pediatr. 2018;60(6):757-761. doi: 10.24953/turkjped.2018.06.022.
9
Sweating blood: history and review.血汗症:历史与综述
CMAJ. 2017 Oct 23;189(42):E1315-E1317. doi: 10.1503/cmaj.170756. Epub 2017 Oct 22.
10
Hematidrosis (bloody sweat): a review of the recent literature (1996-2016).血汗症(血性汗液):近期文献综述(1996 - 2016年)
Acta Dermatovenerol Alp Pannonica Adriat. 2018 Jun;27(2):85-90.