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《血泪:血汗症的罕见病例》

Crimson Tears: A Rare Case of Hematohidrosis.

作者信息

Cherukuru Sreeja, Uppara Shivarama Krishna, Raval Rutvik, Chappidi Mamatha, K Dileep Satya

机构信息

Psychiatry, Sri Venkateswara Medical College, Tirupati, IND.

Pediatrics, Sri Venkateswara Medical College, Tirupati, IND.

出版信息

Cureus. 2024 Aug 30;16(8):e68233. doi: 10.7759/cureus.68233. eCollection 2024 Aug.

Abstract

Hematohidrosis is a rare clinical disorder characterized by oozing blood from intact skin and mucous membranes in the absence of a bleeding disorder. Most of the cases reported are from Asia. Although etiopathogenesis is unclear, it has been strongly linked to psychological stress. A nine-year-old girl was brought to the hospital with multiple episodes of painless bleeding from her nose and mouth for four days and eyes for three days, lasting four to five minutes each. Her symptoms and a thorough but unrevealing workup, including brain imaging, led to a clinical diagnosis of hematohidrosis, with parental disharmony as the underlying stress factor. Family therapy was recommended, and parent management training regarding the positive and negative reinforcement techniques was given. A significant improvement was observed at her one-month follow-up. This case adds to the current limited literature on hematohidrosis, highlighting its association with psychological stress and the importance of a multidisciplinary approach to management. Future research is warranted to elucidate molecular pathways involved in stress-induced vascular dysfunction and explore targeted therapeutic interventions.

摘要

血汗症是一种罕见的临床病症,其特征是在没有出血性疾病的情况下,完整的皮肤和黏膜渗血。报告的大多数病例来自亚洲。尽管发病机制尚不清楚,但它与心理压力密切相关。一名九岁女孩因鼻、口反复无痛出血四天,眼睛出血三天,每次持续四到五分钟,被送往医院。她的症状以及包括脑部成像在内的全面但无结果的检查,导致临床诊断为血汗症,父母关系不和谐是潜在的压力因素。建议进行家庭治疗,并给予父母关于正负强化技术的管理培训。在她一个月的随访中观察到显著改善。该病例补充了目前关于血汗症的有限文献,突出了其与心理压力的关联以及多学科管理方法的重要性。有必要进行未来研究以阐明压力诱导的血管功能障碍所涉及的分子途径,并探索有针对性的治疗干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f74/11439452/99cfc93d2e0b/cureus-0016-00000068233-i01.jpg

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