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全髋关节置换术后镇痛药物使用的比较性综述:阿片类药物与非阿片类药物

Comparative Review of Postoperative Analgesic Use After Total Hip Replacement: Opioids Versus Non-opioids.

作者信息

Singh Gursimran, Dhaniwala Nareshkumar, Jadawala Vivek H, Salwan Ankur, Batra Nitish

机构信息

Orthopaedics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2024 Aug 30;16(8):e68237. doi: 10.7759/cureus.68237. eCollection 2024 Aug.

DOI:10.7759/cureus.68237
PMID:39347367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11439489/
Abstract

Total hip replacement (THR) is a common surgical procedure aimed at alleviating pain and improving function in patients with hip joint pathology. Effective postoperative pain management is crucial for patient recovery, satisfaction, and overall outcomes. This narrative review examines the comparative efficacy, safety, and implications of using opioids versus non-opioid analgesics in managing postoperative pain following THR. Opioids, while effective for severe pain, pose significant risks such as addiction, tolerance, and adverse effects. Non-opioid analgesics, including non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, and regional anesthesia techniques, offer alternatives with potentially fewer side effects. This review synthesizes current evidence from clinical trials, observational studies, and expert guidelines to provide a comprehensive understanding of the benefits and drawbacks of each analgesic approach. The goal is to inform clinical decision-making and optimize pain management strategies for THR patients, balancing efficacy and safety.

摘要

全髋关节置换术(THR)是一种常见的外科手术,旨在缓解髋关节病变患者的疼痛并改善其功能。有效的术后疼痛管理对于患者的康复、满意度及总体预后至关重要。本叙述性综述探讨了在全髋关节置换术后疼痛管理中使用阿片类药物与非阿片类镇痛药的疗效对比、安全性及影响。阿片类药物虽然对重度疼痛有效,但存在成瘾、耐受性及不良反应等重大风险。非阿片类镇痛药,包括非甾体抗炎药(NSAIDs)、对乙酰氨基酚及区域麻醉技术,提供了副作用可能较少的替代方案。本综述综合了来自临床试验、观察性研究及专家指南的现有证据,以全面了解每种镇痛方法的利弊。目标是为临床决策提供依据,并优化全髋关节置换术患者的疼痛管理策略,平衡疗效与安全性。

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Comparative Review of Postoperative Analgesic Use After Total Hip Replacement: Opioids Versus Non-opioids.全髋关节置换术后镇痛药物使用的比较性综述:阿片类药物与非阿片类药物
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本文引用的文献

1
Effectiveness of Intravenous Non-Opioid Analgesics for Postoperative Pain Management of in Patients Undergoing Hip Surgery: A Systematic Review and Meta-Analysis.静脉非阿片类镇痛药在髋关节手术后患者的术后疼痛管理中的有效性:系统评价和荟萃分析。
Medicina (Kaunas). 2023 Oct 27;59(11):1904. doi: 10.3390/medicina59111904.
2
Opioid versus non-opioid postoperative pain management in otolaryngology.耳鼻喉科术后阿片类药物与非阿片类药物疼痛管理。
BMC Anesthesiol. 2023 Aug 25;23(1):291. doi: 10.1186/s12871-023-02213-x.
3
Risk factors for pain after total hip arthroplasty: a systematic review.全髋关节置换术后疼痛的危险因素:一项系统综述。
Arthroplasty. 2023 Apr 3;5(1):19. doi: 10.1186/s42836-023-00172-9.
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Postoperative Pain Management in Enhanced Recovery Pathways.加速康复路径中的术后疼痛管理
J Pain Res. 2022 Jan 13;15:123-135. doi: 10.2147/JPR.S231774. eCollection 2022.
5
The Routes of Administration for Acute Postoperative Pain Medication.急性术后疼痛药物的给药途径
Pain Ther. 2021 Dec;10(2):909-925. doi: 10.1007/s40122-021-00286-5. Epub 2021 Jul 17.
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Advances and innovations in total hip arthroplasty.全髋关节置换术的进展与创新
SICOT J. 2021;7:26. doi: 10.1051/sicotj/2021025. Epub 2021 Apr 12.
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Effectiveness, Safety, and Barriers to Early Mobilization in the Intensive Care Unit.重症监护病房早期活动的有效性、安全性及障碍
Crit Care Res Pract. 2020 Nov 26;2020:7840743. doi: 10.1155/2020/7840743. eCollection 2020.
8
Non-Opioid Perioperative Pain Strategies for the Clinician: A Narrative Review.临床医生的非阿片类围手术期疼痛策略:叙述性综述
Pain Ther. 2020 Jun;9(1):25-39. doi: 10.1007/s40122-019-00146-3. Epub 2020 Jan 13.
9
Regional and Multimodal Analgesia to Reduce Opioid Use After Total Joint Arthroplasty: A Narrative Review.区域和多模式镇痛以减少全关节置换术后阿片类药物的使用:一项叙述性综述
HSS J. 2019 Feb;15(1):57-65. doi: 10.1007/s11420-018-9652-2. Epub 2018 Dec 7.
10
Risk Factors of Neuropathic Pain after Total Hip Arthroplasty.全髋关节置换术后神经性疼痛的危险因素
Hip Pelvis. 2018 Dec;30(4):226-232. doi: 10.5371/hp.2018.30.4.226. Epub 2018 Dec 6.