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并非良性(错误)标签:非过敏专家的青霉素过敏教育。

Not a Benign (Mis)Label: Penicillin Allergy Education for the Nonallergist.

机构信息

Clinical Fellow, Division of Allergy, Pulmonology, and Critical Care, Vanderbilt University Medical Center.

Associate Professor of Pediatrics and Anesthesiology, Vanderbilt University Medical Center.

出版信息

MedEdPORTAL. 2024 Sep 27;20:11440. doi: 10.15766/mep_2374-8265.11440. eCollection 2024.

DOI:10.15766/mep_2374-8265.11440
PMID:39347473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11427523/
Abstract

INTRODUCTION

Up to 20% of the US population carries a penicillin allergy label; however, over 95% of those patients can safely tolerate penicillin. This discrepancy has important personal and public health consequences. There is no published curriculum for medical trainees that covers penicillin allergy history taking, risk assessment, and antibiotic prescribing.

METHODS

We created a 60-minute, interactive curriculum that targeted medical students during their internal medicine rotation. We employed learning strategies including didactics, case-based learning, and role-playing. We compared self-efficacy and knowledge before and after the intervention using paired tests.

RESULTS

A total of 28 medical students participated, with 25 completing both the pre- and postworkshop surveys. There was a statistically significant improvement in student-rated preparedness to prescribe antibiotics to patients with a penicillin allergy label ( < .001) and determine whether a patient has a history of an allergic reaction that was severe or life-threatening ( < .001). There was additionally a statistically significant increase in students' perception that penicillin allergy labels carry important health consequences ( = .005), as well as increase in their total knowledge scores ( = .006).

DISCUSSION

The workshop employs adult learning techniques to improve self-efficacy and knowledge regarding penicillin allergy in medical students. Further work is needed to refine the curriculum, seek external validity, and determine the impact of this workshop on clinical outcomes.

摘要

简介

美国有 20%的人口携带青霉素过敏标签;然而,超过 95%的患者可以安全耐受青霉素。这种差异对个人和公共健康都有重要影响。目前没有针对医学实习生的涵盖青霉素过敏史采集、风险评估和抗生素处方的公开课程。

方法

我们为内科轮转的医学生创建了一个 60 分钟的互动课程。我们采用了教学法、案例学习和角色扮演等学习策略。我们使用配对检验比较干预前后的自我效能感和知识。

结果

共有 28 名医学生参与,其中 25 名学生完成了预调查和后调查。学生对准备为带有青霉素过敏标签的患者开抗生素处方的自评( <.001)和确定患者是否有过严重或危及生命的过敏反应史的自评( <.001)均有统计学意义上的显著提高。学生们还认为青霉素过敏标签具有重要的健康后果( =.005),以及他们的总知识得分( =.006)均有统计学意义上的显著提高。

讨论

该研讨会采用成人学习技术,提高医学生对青霉素过敏的自我效能感和知识。需要进一步工作来完善课程,寻求外部有效性,并确定该研讨会对临床结果的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cb/11427523/d1588055ad25/mep_2374-8265.11440-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cb/11427523/2fb5402f4846/mep_2374-8265.11440-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cb/11427523/2ca01da7069d/mep_2374-8265.11440-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cb/11427523/d1588055ad25/mep_2374-8265.11440-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cb/11427523/2fb5402f4846/mep_2374-8265.11440-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cb/11427523/2ca01da7069d/mep_2374-8265.11440-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42cb/11427523/d1588055ad25/mep_2374-8265.11440-g003.jpg

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本文引用的文献

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Penicillin Allergy Label Is Associated With Worse Clinical Outcomes in Bacterial Pneumonia.青霉素过敏标签与细菌性肺炎的临床结局较差相关。
J Allergy Clin Immunol Pract. 2022 Dec;10(12):3262-3269. doi: 10.1016/j.jaip.2022.08.027. Epub 2022 Sep 28.
2
Drug allergy: A 2022 practice parameter update.药物过敏:2022年实践参数更新
J Allergy Clin Immunol. 2022 Dec;150(6):1333-1393. doi: 10.1016/j.jaci.2022.08.028. Epub 2022 Sep 17.
3
Instruction and Simulation to Improve Pharmacy Students' Knowledge and Confidence Regarding Assessment of Penicillin Allergies.
指导和模拟以提高药学学生评估青霉素过敏的知识和信心。
Am J Pharm Educ. 2022 Mar;86(3):8688. doi: 10.5688/ajpe8688. Epub 2021 Jul 22.
4
Development and Validation of a Penicillin Allergy Clinical Decision Rule.开发和验证青霉素过敏临床决策规则。
JAMA Intern Med. 2020 May 1;180(5):745-752. doi: 10.1001/jamainternmed.2020.0403.
5
Penicillin Allergy.青霉素过敏
N Engl J Med. 2019 Dec 12;381(24):2338-2351. doi: 10.1056/NEJMra1807761.
6
Utilization of high-fidelity simulation to address challenges with the basic science immunology education of preclinical medical students.利用高保真模拟来解决临床前医学学生基础科学免疫学教育中的挑战。
BMC Med Educ. 2019 Sep 14;19(1):352. doi: 10.1186/s12909-019-1786-5.
7
Risk of meticillin resistant and in patients with a documented penicillin allergy: population based matched cohort study.有青霉素过敏史患者罹患耐甲氧西林金黄色葡萄球菌和 感染的风险:基于人群的匹配队列研究。
BMJ. 2018 Jun 27;361:k2400. doi: 10.1136/bmj.k2400.
8
The Impact of a Reported Penicillin Allergy on Surgical Site Infection Risk.报告青霉素过敏对手术部位感染风险的影响。
Clin Infect Dis. 2018 Jan 18;66(3):329-336. doi: 10.1093/cid/cix794.
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The Cost of Self-Reported Penicillin Allergy: A Systematic Review.自述青霉素过敏的代价:系统评价。
J Allergy Clin Immunol Pract. 2018 Sep-Oct;6(5):1649-1654.e4. doi: 10.1016/j.jaip.2017.12.033. Epub 2018 Jan 31.
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