利用 MALDI-MSI 测定新型前列腺癌组织芯片中 N-糖链和胶原蛋白/细胞外基质蛋白的组成。
Determining the N-Glycan and Collagen/Extracellular Matrix Protein Compositions in a Novel Outcome Cohort of Prostate Cancer Tissue Microarrays Using MALDI-MSI.
机构信息
Medical University of South Carolina, Charleston, South Carolina.
University of Texas Health Science Center, San Antonio, Texas.
出版信息
Cancer Res Commun. 2024 Nov 1;4(11):3036-3048. doi: 10.1158/2767-9764.CRC-24-0152.
Abstract
Using matrix-assisted laser desorption/ionization mass spectrometry imaging techniques on a unique cohort of prostate cancer tissues, we highlighted several molecular characteristics of matrix that have potential to act as early predictors of prostate cancer metastasis.
摘要
利用基质辅助激光解吸/电离质谱成像技术对一组独特的前列腺癌组织进行研究，我们强调了基质的几个分子特征，这些特征有可能成为前列腺癌转移的早期预测因子。
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